2359-11-7

Basic information

• Product Name: 1-oxa-4-azaspiro[4.5]decan-4-ethanol
• Synonyms: 1-oxa-4-azaspiro[4.5]decan-4-ethanol;1-Oxa-4-azaspiro[4.5]decane-4-ethanol
• CAS NO: 2359-11-7
• Molecular Formula: C₁₀H₁₉NO₂
• Molecular Weight: 185.26336
• EINECS: 219-101-8
• Mol File: 2359-11-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 310.2°Cat760mmHg
• Flash Point: 141.4°C
• Appearance: /
• Density: 1.1g/cm³
• Vapor Pressure: 5.46E-05mmHg at 25°C
• Refractive Index: 1.526
• CAS DataBase Reference: 1-oxa-4-azaspiro[4.5]decan-4-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-oxa-4-azaspiro[4.5]decan-4-ethanol(2359-11-7)
• EPA Substance Registry System: 1-oxa-4-azaspiro[4.5]decan-4-ethanol(2359-11-7)

Safety Data

• Hazardous Substances Data: 2359-11-7(Hazardous Substances Data)

Usage

Flammability and Explosibility

Notclassified

InChI:InChI=1/C10H19NO2/c12-8-6-11-7-9-13-10(11)4-2-1-3-5-10/h12H,1-9H2

Upstream product

• 108-94-1 cyclohexanone 
• 111-42-2 2,2'-iminobis[ethanol] 
• 1670-47-9 1,1-diethoxycyclohexane 

Downstream Products

• 87298-93-9 2-(1-Oxa-4-aza-spiro[4.5]dec-4-yl)-ethanol; compound with (4-chloro-phenylsulfanyl)-acetic acid 
• 122-96-3 1,4-bis(2-hydroxyethyl)piperazine 
• 108-94-1 cyclohexanone 
• 51265-34-0 N-(2-hydroxyethyl)-4,5,6,7-tetrahydro-1H-indole 
• 111-42-2 2,2'-iminobis[ethanol] 
• 108-93-0 cyclohexanol 

Relevant articles and documents

PREPARATION OF DELMOPINOL

It comprises a process for the production of delmopinol or a pharmaceutically acceptable salt and/or a solvate thereof, by subjecting the compound of formula (II) where R1 and R2 are the same or different, independently selected from the group consisting of H, (C1-C6) alkyl or, alternatively, R1 and R2 form, together with the carbon atom to which they are attached, a (C5-C6) cycloalkyl radical; and R3 is a radical selected from the group consisting of CF3, (C1-C4) alkyl, phenyl, and phenyl mono- ordisubstituted by a radical selected from the group consisting of (C1-C4)-alkyl, halogen and nitro to a deprotection and cyclisation reaction. The process is useful to prepare delmopinol or its salts on an industrial scale. The compound of formula (II) is new and also forms part of the present invention, as well as its preparation process and other new intermediates of said preparation process. .

SYNTHESIS AND BIOLOGICAL ACTIVITY OF 2-HYDROXYALKYLAMMONIUM SALTS OF ACETIC ACIDS

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