5129-79-3

Upstream product

• 123-39-7 N-Methylformamide 
• 107-30-2 chloromethyl methyl ether 
• 2143-68-2 methoxyl radical 
• 68-12-2 N,N-dimethyl-formamide 
• 335344-28-0 N‐methoxymethyl‐N‐methylcarbamoyl(trimethyl)silane 
• 67-56-1 methanol 
• 5129-76-0 N-formyloxymethyl-N-methylformamide 

Relevant academic research and scientific papers

Lignin-fueled photoelectrochemical platform for light-driven redox biotransformation

The valorization of lignin has significant potential in producing commodity chemicals and fuels from renewable resources. However, the catalytic degradation of lignin is kinetically challenging and often requires noble metal catalysts to be used under harsh and toxic conditions. Here, we report the bias-free, solar reformation of lignin coupled with redox biotransformation in a tandem structure of a BiVO4 photoanode and perovskite photovoltaic. The tandem structure compensates for the potential gap between lignin oxidation and biocatalytic reduction through artificial Z-schematic absorption. We found that the BiVO4-catalyzed photoelectrochemical oxidation of lignin facilitated the fragmentation of higher molecular weight lignin into smaller carboxylated aliphatic and aromatic acids. Lignin oxidation induced photocurrent generation at the photoanode, which enabled efficient electroenzymatic reactions at the cathode. This study successfully demonstrates the oxidative valorization of lignin as well as biocatalytic reductions (e.g., CO2-to-formate and α-ketoglutarate-to-l-glutamate) in an unbiased biocatalytic PEC platform, which provides a new strategic approach for photo-biocatalysis using naturally abundant renewable resources.

α-Alkoxycarbonyl-α-hydroxy secondary amides from a carbamoylsilane and α-ketoesters

The addition of N-methoxymethyl-N-organylcarbamoyl(trimethyl)silane to α-ketoesters in anhydrous toluene at 60 °C afforded α-alkoxycarbonyl-α-siloxy amides in high yields (75–96%). The methoxymethyl was used as an amino protecting group and could be easily converted into hydrogen atom by simple acid hydrolysis leading to α-alkoxycarbonyl-α- hydroxy secondary amides.

PROCESS FOR PRODUCING TRICYCLIC KETONE

In order to efficiently supply CPT, which is a starting compound of irinotecan hydrochloride and a variety of camptothecin derivatives, by a practical total synthesis, the invention provides a means of efficiently preparing a tricyclic ketone that corresp

Direct vs. Indirect Mechanisms in Organic Electrochemistry. Estimates of Activation Energies for Hydrogen Atom Transfer Processes of Relevance in Indirect Mechanisms Using the Bond Energy-Bond Order (BEBO) and Equibonding Methods

Activation energies for a number of hydrogen abstraction reactions of interest in mechanistic organic electrochemistry have been calculated using the bond energy-bond-order (BEBO) and equibonding method.The main emphasis has been put on processes with bearing on the problem of deciding between direct and indirect mechanisms in anodic oxidation, viz. acyloxylation, hydroxylation, methoxylation, nitrooxylation, cyanation, carbomethoxylation and azidation.The results indicate that indirect mechanisms might play a more important role than presently assumed.