51297-43-9

Upstream product

• 110-89-4 piperidine 
• 78-94-4 methyl vinyl ketone 

Downstream Products

• 78975-75-4 1-Phenyl-1,4,8-nonantrion 
• 78975-61-8 3-Methyl-2-(2-oxopropyl)-2-cyclohexen-1-on 
• 78975-59-4 3-Methyl-2-(2-oxohexyl)-2-cyclohexen-1-on 
• 78975-58-3 3-Methyl-2-(2-oxoheptyl)-2-cyclohexen-1-on 
• 78975-57-2 3-Methyl-2-(2-oxooctyl)-2-cyclohexen-1-on 
• 78975-65-2 5-Methyl-3-phenyl-5,6,7,8-tetrahydrocinnolin 
• 78975-55-0 2-<2-(2-Furyl)-2-oxoethyl>-3-methyl-2-cyclohexen-1-on 
• 78975-56-1 3-Methyl-2-(2-oxotridecyl)-2-hexen-1-on 
• 78975-60-7 3-Methyl-2-(2-oxopentyl)-2-cyclohexen-1-on 

Relevant academic research and scientific papers

Supported Gold Nanoparticles for Efficient α-Oxygenation of Secondary and Tertiary Amines into Amides

Although the α-oxygenation of amines is a highly attractive method for the synthesis of amides, efficient catalysts suited to a wide range of secondary and tertiary alkyl amines using O2as the terminal oxidant have no precedent. This report describes a novel, green α-oxygenation of a wide range of linear and cyclic secondary and tertiary amines mediated by gold nanoparticles supported on alumina (Au/Al2O3). The observed catalysis was truly heterogeneous, and the catalyst could be reused. The present α-oxygenation utilizes O2as the terminal oxidant and water as the oxygen atom source of amides. The method generates water as the only theoretical by-product, which highlights the environmentally benign nature of the present reaction. Additionally, the present α-oxygenation provides a convenient method for the synthesis of18O-labeled amides using H218O as the oxygen source.