51310-26-0Relevant articles and documents
Synthesis of substituted indene derivatives via silver-catalyzed annulative 1:1 coupling of secondary benzyl alcohols with alkynes
Morisaka, Hideaki,Hirosawa, Keishi,Inai, Yasuhito,Usuki, Yoshinosuke,Satoh, Tetsuya
supporting information, p. 456 - 458 (2021/03/16)
The annulative coupling of secondary benzyl alcohols with internal alkynes efficiently proceeds in the presence of a silver catalyst. The reaction gives 1,2,3-substituted indene derivatives selectively as 1:1 coupling products. The procedure provides a straightforward synthetic route to indenes from readily available starting materials upon treatment with a simple reaction system under mild conditions.
Asymmetric hydrogenation of allylic alcohols using ir?N,P-Complexes
Li, Jia-Qi,Liu, Jianguo,Krajangsri, Suppachai,Chumnanvej, Napasawan,Singh, Thishana,Andersson, Pher G.
, p. 8342 - 8349 (2018/05/23)
In this study, a series of γ,γ-disubstituted and β,γ-disubstituted allylic alcohols were prepared and successfully hydrogenated using suitable N,P-based Ir complexes. High yields and excellent enantioselectivities were obtained for most of the substrates studied. This investigation also revealed the effect of the acidity of the N,P?Ir-complexes on the acid-sensitive allylic alcohols. DFT ΔpKa calculations were used to explain the effect of the N,P-ligand on the acidity of the corresponding Ir-complex. The selectivity model of the reaction was used to accurately predict the absolute configuration of the hydrogenated alcohols.
Synthesis of substituted indenes through iron-catalyzed annulation of benzylic alcohols with alkynes
Bu, Xiuli,Hong, Jianquan,Zhou, Xigeng
supporting information; scheme or table, p. 2111 - 2118 (2011/10/09)
A convenient and efficient method for the synthesis of polysubstituted indenes has been developed by the iron(III) trichloride-catalyzed tandem mono- and dibenzylation/cyclization reactions of benzylic alcohols with alkynes. This method is featured with the easily available starting materials, cheap catalyst, simple manipulation and mild conditions. Copyright
Efficient synthesis of indenes by FeCl3·6H2O-catalyzed intramolecular Friedel-Crafts reaction of aryl-substituted allylic alcohols
Wang, Jialiang,Zhang, Lixin,Jing, Yufeng,Huang, Wen,Zhou, Xigeng
experimental part, p. 4978 - 4982 (2009/12/01)
An efficient procedure for the synthesis of substituted indenes through the FeCl3·6H2O-catalyzed intramolecular Friedel-Crafts cyclization of aryl-substituted allylic alcohols has been developed. This method features the easily avail
Reactions of α-Oxoketenedithioacetals with Phenylmagnesium Bromide: Synhesis of Novel 1-Phenyl-1-methylthio-3-phenyl (or 2,3-Fused)-indenes and 2,3-Fused Heterocyclic-1,3-Diphenyl-2-alken-1-ones
Singh, Gurdeep,Ila, Hiriyakkanawar,Junjappa, Hiriyakkanawar
, p. 744 - 747 (2007/10/02)
Novel substituted and 1-methylthio-1-phenylindenes have been synthesised by boron trifluoride etherate cyclocondensations of the corresponding carbinol acetals obtained by sequential 1,4 and 1,2 additions of phenylmagnesium bromide to α-oxoketenedithioacetals.Some of these indenes have been desulphurized to give the parent ring systems.Synthesis of novel 2,3-fused heterocyclic 1,3-diphenyl-alken-1-ones by boron trifluoride-ether catalyzed methanolysis of the corresponding carbinol acetals has also been described.
SYNTHESIS OF INDENES FROM PHENYLPROPANONES USING ALUMINA CATALYST
Jayamani, M.,Pant, Nalin,Ananthan, S.,Narayanan, K.,Pillai, C. N.
, p. 4325 - 4332 (2007/10/02)
1,3-Diphenylpropan-2-one undergoes dehydration over alumina at around 400 deg C to form 1,3-diphenylallene which cyclizes to 2-phenylindene.Since the parent ketone can be obtained under the reaction conditions from phenylacetic acid, the present reaction forms a one step syntheses of 2-phenylindene from phenylacetic acid. 3- and 4-methylphenylacetic acids also give the corresponding indenes. 1,3-Diphenylpropan-1-ones also give phenylindenes, presumably by a direct cyclodehydration reaction.
Ozonolysis of a Series of 1-Substituted Indenes. The Substituent Steric Effects on Ozonide Exo/Endo Ratios
Miura, Masahiro,Nojima, Masatomo,Kusabayashi, Shigekazu,McCullough, Kevin J.
, p. 2932 - 2936 (2007/10/02)
The ozonolysis of a series of disubstituted (1,2 and 1,3) and trisubstituted (1,2,3) indenes 1-28 in carbon tetrachloride at 20 deg C has been investigated.The major product in each case was the corresponding bicyclic ozonide, usually obtained as a mixtur
Sigmatropic Indenyl Rearrangements Induced by Electronic Excitation
Padwa, Albert,Goldstein, Steven,Loza, Roman,Pulwer, Mitchell
, p. 1858 - 1868 (2007/10/02)
The photochemical rearrangement of several arylalkyl substituted indenes has been studied.The rearrangements were shown to be derived from the ?,?* singlet state since triplet sensitization led to no reaction or else resulted in a Paterno-Buchi
Photosensitized Electron-Transfer-Induced Reactions of Some Cyclopropene Derivatives
Padwa, Albert,Chou, Chuen S.,Rieker, William F.
, p. 4555 - 4564 (2007/10/02)
The 9,10-dicyanoanthracene-sensitized rearrangement of several 3-phenyl-substituted cyclopropenes to indenes in acetonitrile has been studied. When an unsymmetrically 1-phenyl-2-methyl-substituted cyclopropene was used, the major indene obtained correspon
