51315-07-2

Usage

Uses

Used in Pharmaceutical Industry:
2-Cyano-3-nitropyridine is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Cyano-3-nitropyridine is utilized as an intermediate for the production of pesticides and other agrochemicals, contributing to the development of effective solutions for crop protection and management.
Used in Organic Synthesis:
2-Cyano-3-nitropyridine is employed as a building block in organic synthesis for the creation of various substituted pyridine derivatives. Its presence in these compounds can enhance their chemical properties and potential applications in different fields.
Safety Precautions:
When handling 2-Cyano-3-nitropyridine, it is essential to take necessary safety measures, such as wearing protective clothing, gloves, and eye protection, to minimize the risk of skin and eye irritation. Additionally, it should be stored and used in a well-ventilated area, away from heat sources or direct sunlight, to prevent any hazardous incidents.

InChI:InChI=1/C4H2ClIN2/c5-4-3(6)1-7-2-8-4/h1-2H

Upstream product

• 6332-56-5 2-hydroxy-3-nitropyridine 
• 5470-18-8 2-Chloro-3-nitropyridine 
• 19755-53-4 2-bromo-3-nitropyridine 
• 4214-75-9 2-amino-3-nitropyridine 

Downstream Products

• 1416371-39-5 C₁₅H₁₀N₄S 
• 1416371-40-8 C₁₆H₁₂N₄OS 
• 1416371-41-9 C₁₇H₁₄N₄O₂S 
• 1416371-42-0 C₁₇H₁₄N₄O₂S 
• 1416371-43-1 C₁₈H₁₆N₄O₃S 
• 1416371-46-4 C₁₅H₈BrFN₄S 
• 1416371-47-5 C₁₅H₉N₅O₃S 
• 342816-54-0 3-ethylsulfanylpyridine-2-carbonitrile 
• 42242-11-5 3-aminopyridine-2-carbonitrile 
• 932-35-4 3-hydroxypyridine-2-carbonitrile 
• 97509-75-6 3-fluoropicolinonitrile 
• 24059-89-0 3-methoxy-pyridine-2-carbonitrile 
• 59290-92-5 3-Nitropyridin-2-carboxamid 

Relevant academic research and scientific papers

METHOD OF PRODUCING PYRIDINE COMPOUND

PROBLEM TO BE SOLVED: To provide a method of producing a pyridine compound of formula (1) represented by 2-cyano-3-ethylthiopyridine. SOLUTION: A method of producing a pyridine compound represented by formula (1) comprises the step for a reaction between a compound represented by formula (4) and a compound represented by formula (5), wherein R2-R4 are H or the like; R1 is a chain hydrocarbon group or the like; and M is an alkali metal atom. COPYRIGHT: (C)2016,JPOandINPIT

Synthesis and biological evaluation of N-arylbenzo[b]thieno[3,2-d] pyrimidin-4-amines and their pyrido and pyrazino analogues as Ser/Thr kinase inhibitors

A useful and rapid access to libraries of N-arylbenzo[b]thieno[3,2-d] pyrimidin-4-amines and their pyrido and pyrazino analogues was designed and optimized for the first time via microwave-accelerated condensation and Dimroth rearrangement of the starting anilines with N′-(2-cyanoaryl)-N,N- dimethylformimidamides obtained by reaction of thiophene precursors with dimethylformamide dimethylacetal. The inhibitory potency of the final products against five protein kinases (CDK5/p25, CK1δ/ε, GSK3α/β, DYRK1A and CLK1) was estimated. N-arylpyrido[3′,2′:4,5]thieno[3,2-d] pyrimidin-4-amine series of compounds (4a-j) turned out to be particularly promising for the development of new pharmacological inhibitors of CK1 and CLK1 kinases.