932-35-4Relevant articles and documents
POLYCYCLIC N-HETEROCYCLIC COMPOUNDS. 49 NEW SYNTHETIC METHOD OF FURONAPHTHYRIDINE SKELETON
Hirota, Takashi,Matsushita, Tetsuo,Sasaki, Kenji,Kashino, Setsuo
, p. 2565 - 2574 (1995)
An synthesis of 5-amino-1,2-dihydrofuronaphthyridine (6) from 3-(3-cyanopropoxy)pyridine-2-carbonitrile (5) is described.Compound (6) was converted to mother skeleton (12).Treatment of 6 with conc. hydrochloric acid gave new spiroheterocycle (7).
PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-ACETOXYPICOLINIC ACIDS
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, (2019/01/05)
4-Alkoxy-3-hydroxypicolinic acids may be conveniently prepared from 4,6-dibromo-3-hydroxypicolinonitrile in a series of chemical steps selected from bromo substitution, nitrile hydrolysis and halogen reduction that are conducted as a single pot process. 4,6-Dibromo-3-hydroxypicolinonitrile may be prepared from furfural in a series of chemical steps selected from cyano-amination, amine salt formation and bromination-rearrangement. 4-Alkoxy-3-acetoxypicolinic acids may be conveniently prepared from 4-alkoxy-3-hydroxypicolinic acids by treatment with acetic anhydride.
PROCESS FOR THE PREPARATION OF 4-ALKOXY-3-ACETOXYPICOLINIC ACIDS
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, (2017/08/20)
4-Alkoxy-3-hydroxypicolinic acids may be conveniently prepared from 4,6-dibromo-3-hydroxypicolinonitrile in a series of chemical steps selected from bromo substitution, nitrile hydrolysis and halogen reduction that are conducted as a single pot process. 4,6-Dibromo-3-hydroxypicolinonitrile may be prepared from furfural in a series of chemical steps selected from cyano-amination, amine salt formation and bromination-rearrangement. 4-Alkoxy-3-acetoxypicolinic acids may be conveniently prepared from 4-alkoxy-3-hydroxypicolinic acids by treatment with acetic anhydride.