51315-69-6

Basic information

• Product Name: Benzenesulfonamide, 4-methyl-N-[2-(2-propenyl)phenyl]-
• CAS NO: 51315-69-6
• Molecular Formula: C16H17NO2S
• Molecular Weight: 287.382
• Mol File: 51315-69-6.mol
• Article Data: 28

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, 4-methyl-N-[2-(2-propenyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 4-methyl-N-[2-(2-propenyl)phenyl]-(51315-69-6)
• EPA Substance Registry System: Benzenesulfonamide, 4-methyl-N-[2-(2-propenyl)phenyl]-(51315-69-6)

Safety Data

• Hazardous Substances Data: 51315-69-6(Hazardous Substances Data)

Upstream product

• 593-60-2 Vinyl bromide 
• 589-09-3 N-allyl-N-phenylamine 
• 32704-22-6 2-allyl-phenylamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 104-15-4 toluene-4-sulfonic acid 
• 62-53-3 aniline 
• 615-43-0 2-iodophenylamine 
• 73396-92-6 2-iodo-N,N-diallylaniline 
• 1627211-04-4 C₁₅H₁₉N 

Downstream Products

• 1094359-10-0 (S)-2-(2,2,6,6-tetramethyl-piperidin-1-yloxymethyl)-1-(toluene-4-sulfonyl)-2,3-dihydro-1H-indole 
• 1309578-93-5 methyl 2-(1-tosylindolin-2-yl)acetate 
• 1309578-55-9 C₁₈H₁₉NO₄S 
• 1309578-43-5 (E)-methyl 4-(2-(4-methylphenylsulfonamido)phenyl)but-2-enoate 
• 1309578-86-6 (Z)-Methyl 4-(2-(4-methylphenylsulfonamido)phenyl)but-2-enoate 
• 1258868-65-3 ethyl (E)-4-[2-(4-methylphenylsulfonamido)phenyl]but-2-enoate 
• 166048-19-7 2-(1-tosylindolin-2-yl)acetaldehyde 

Relevant articles and documents

Intramolecular Aminoazidation of Unactivated Terminal Alkenes by Palladium-Catalyzed Reactions with Hydrogen Peroxide as the Oxidant

The palladium-catalyzed aminoazidation of aminoalkenes yielding azidomethyl-substituted nitrogen-containing heterocycles was developed. The procedure requires oxidative conditions and occurs at room temperature in the presence of hydrogen peroxide and NaN3 as the azide source. These conditions provide selective exo-cyclization/azidation of the carbon-carbon double bond, furnishing a versatile approach toward five-, six-, and seven-membered heterocyclic rings.

Synthesis of Benzofuran and Indole Derivatives Catalyzed by Palladium on Carbon

Benzofurans and indoles are key moieties in many natural products and pharmaceuticals. Herein, we describe a cheap and easy-to-execute strategy for the synthesis of benzofurans and indoles, employing Pd/C as the promoter. A variety of substituted allyl-anilines and allyl-phenols were converted into the desired products in good to excellent yields. Recycling of Pd/C was possible up to five cycles, keeping similar levels of reactivity.

Enantioselective Synthesis of 2-Bromomethyl Indolines via BINAP(S)-Catalyzed Bromoaminocyclization of Allyl Aniline

An enantioselective bromoamination of allyl aniline with N-bromosuccinimide (NBS) catalyzed by BINAP(S) (BINAP monosulfide) is described. This protocol could provide a range of chiral 2-bromomethyl indolines in good to excellent yields with up to 87% ee.