51323-70-7Relevant academic research and scientific papers
The rapid synthesis of organic compounds in microwave ovens. II
Gedye, Richard N.,Rank, Werner,Westaway, Kenneth
, p. 706 - 711 (2007/10/02)
Using microwaves to carry out organic reactions does not significantly alter the product composition.The small changes in product composition that are observed when microwaves are used arise because the microwave reactions occur at higher temperatures than reflux reactions.The results demonstrate that ions in the reaction mixture alter the heating rate of the microwave reactions.Although scaling-up the reaction leads to slightly lower rate reaction (lower percentage yield), one still retains large rate enhancements.
ALKYLATIONS EN ABSENCE DE SOLVANT ORGANIQUE-3. PREPARATION D'ETHERS ALIPHATIQUES PAR ALKYLATION DES ALCOOLATES DANS DES CONDITIONS DOUCES ET ECONOMIQUES.
Barry, J.,Bram, G.,Decodts, G.,Loupy, A.,Pigeon, P,Sansoulet, J.
, p. 2945 - 2950 (2007/10/02)
n-Octyl ethers are obtained by reacting n-octyl halides with performed alkoxides, or better, prepared in situ from ROH and solid KOH.Reactions are performed without any solvent but in the presence of a catalytic amount of tetra-alkyl ammonium salt (Aliquat 366).Good yields (>=92percent for primary R) are obtained at moderate temperatures and with easy work up; for t-C4H9O, elimination is a side reaction, and the effects of temperature and of the nature of the leaving group were examined, so that t-C4H9OC8H17 could then be obtained (yield 77percent) within 20 h at 36 deg C from n-octyl tosylate.
