51332-24-2 Usage
General Description
4-Bromo-N,N-dimethyl-3-(trifluoromethyl)aniline is a chemical compound that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is a brominated aniline derivative with a trifluoromethyl group, making it valuable for its diverse reactivity and potential application in drug discovery and development. 4-BROMO-N,N-DIMETHYL-3-(TRIFLUOROMETHYL)ANILINE is most often utilized in organic synthesis and industrial processes due to its unique properties and reactivity. Additionally, its trifluoromethyl substituent makes it an important building block for the production of fluorinated compounds, which are of interest in drug design and optimization for a range of therapeutic indications. Overall, 4-Bromo-N,N-dimethyl-3-(trifluoromethyl)aniline is a valuable chemical reagent with widespread use in the pharmaceutical and agrochemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 51332-24-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,3,3 and 2 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 51332-24:
(7*5)+(6*1)+(5*3)+(4*3)+(3*2)+(2*2)+(1*4)=82
82 % 10 = 2
So 51332-24-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H9BrF3N/c1-14(2)8-4-3-6(10)5-7(8)9(11,12)13/h3-5H,1-2H3
51332-24-2Relevant articles and documents
Synthesis of Halogenated Anilines by Treatment of N, N-Dialkylaniline N-Oxides with Thionyl Halides
Reed, Hayley,Paul, Tyler R.,Chain, William J.
, p. 11359 - 11368 (2018/08/06)
The special reactivity of N,N-dialkylaniline N-oxides allows practical and convenient access to electron-rich aryl halides. A complementary pair of reaction protocols allow for the selective para-bromination or ortho-chlorination of N,N-dialkylanilines in up to 69% isolated yield. The generation of a diverse array of halogenated anilines is made possible by a temporary oxidation level increase of N,N-dialkylanilines to the corresponding N,N-dialkylaniline N-oxides and the excision of the resultant weak N-O bond via treatment with thionyl bromide or thionyl chloride at low temperature.
