51337-35-0Relevant academic research and scientific papers
Reaction of (chloro carbonyl) phenyl ketene with 5-amino pyrazolones: Synthesis, characterization and theoretical studies of 7-hydroxy-6-phenyl-3-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidine-2,5(1H,4H)-dione derivatives
Zahedifar, Mahboobeh,Razavi, Razieh,Sheibani, Hassan
, p. 730 - 735 (2016)
New 7-hydroxy-6-phenyl-3-(phenyldiazenyl)pyrazolo[1,5-a]pyrimidine-2,5(1H,4H)-dione derivatives were synthesized from the reaction of (chlorocarbonyl)phenyl ketene and 5-amino pyrazolones in high to excellent yields and short reaction times. Structures of
Preparation of 1-(4-methoxyphenyl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-ones as potent, selective and bioavailable inhibitors of coagulation factor Xa
Fevig, John M.,Cacciola, Joseph,Buriak Jr., Joseph,Rossi, Karen A.,Knabb, Robert M.,Luettgen, Joseph M.,Wong, Pancras C.,Bai, Stephen A.,Wexler, Ruth R.,Lam, Patrick Y.S.
, p. 3755 - 3760 (2007/10/03)
Previously, potent factor Xa inhibitors were described based on a pyrazole core. Modifications of the pyrazole core have provided additional novel, highly potent factor Xa inhibitors. This manuscript will describe the synthesis and biological activity of
