51350-23-3

Basic information

• Product Name: p-Hydroxybiphenylacetic acid
• Synonyms: p-Hydroxybiphenylacetic acid;4-Hydroxy-biphenyl-4acetic acid;[1,1-BIPHENYL]-4-ACETIC ACID,4-HYDROXY-
• CAS NO: 51350-23-3
• Molecular Formula: C₁₄H₁₂O₃
• Molecular Weight: 228.24
• Mol File: 51350-23-3.mol

Chemical Properties

• Boiling Point: 435°Cat760mmHg
• Flash Point: 231°C
• Appearance: /
• Density: 1.263g/cm³
• CAS DataBase Reference: p-Hydroxybiphenylacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: p-Hydroxybiphenylacetic acid(51350-23-3)
• EPA Substance Registry System: p-Hydroxybiphenylacetic acid(51350-23-3)

Safety Data

• Hazardous Substances Data: 51350-23-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
p-Hydroxybiphenylacetic acid is used as a building block for the synthesis of pharmaceuticals due to its versatile chemical structure and potential biological activities, including anti-inflammatory and antioxidant properties.
Used in Chemical Industry:
p-Hydroxybiphenylacetic acid is used as a precursor for the synthesis of fragrance compounds, leveraging its chemical properties to create a variety of scented products.
Used in Drug Delivery Systems:
p-Hydroxybiphenylacetic acid is utilized in the development of drug delivery systems to enhance the efficacy and targeted delivery of pharmaceutical agents, taking advantage of its chemical properties to improve therapeutic outcomes.
Overall, p-Hydroxybiphenylacetic acid is a promising compound with diverse applications in the pharmaceutical and chemical industries, offering potential benefits in the synthesis of new drugs, fragrances, and advanced drug delivery systems.

Upstream product

• 1878-68-8 2-(4-bromophenyl)-acetic acid 
• 41841-16-1 (4-bromo-phenyl)-acetic acid methyl ester 
• 13021-18-6 1-(4'-methoxy-biphenyl-4-yl)-ethanone 
• 60277-22-7 2-(4'-methoxy-[1,1'-biphenyl]-4-yl)acetic acid 
• 352652-78-9 methyl (4'-methoxy-1,1'-biphenyl-4-yl) acetate 
• 792945-60-9 4-[(4'-methoxy-biphenyl-4-yl)-thioacetyl]-morpholine 

Downstream Products

• 60277-36-3 4-(5-Chloro-2-methoxy-anilino-carbonyl-methyl)-4'-hydroxybiphenyl 
• 873011-21-3 methyl (4'-hydroxy-1,1'-biphenyl-4-yl)acetate 
• 60277-67-0 2-{4'-[(5-Chloro-2-methoxy-phenylcarbamoyl)-methyl]-biphenyl-4-yloxy}-2-methyl-propionic acid ethyl ester 

Relevant articles and documents

TISSUE FACTOR PRODUCTION INHIBITOR

A medicament which has an activity of inhibiting production of tissue factor and comprises an LXR ligand as an active ingredient; and a medicament for treatment and/or prophylaxis of vascular restenosis following angioplasty, endarterectomy, percutaneous transluminal coronary angioplasty (PTCA) or stent implantation, or treatment and/or prophylaxis of blood coagulation diseases, diseases induced by platelet aggregation including stable or unstable angina pectoris, cardiovascular and cerebrovascular diseases including thromboembolism formation diseases accompanying diabetes, rethrombosis following thrombolysis, cerebral ischemic attack, infarction, stroke, ischemia-derived dementia, peripheral artery disease, thromboembolism formation diseases during use of an aorta-coronary artery bypass, glomerulosclerosis, renal embolism, tumor or cancer metastasis, which comprises an LXR ligand as an active ingredient.

SUBSTITUTED INDOLE COMPOUND

Disclosed is an excellent LXR modulator. A compound represented by the general formula (I): (I) wherein R1, R2, R3 and R4: H, an alkyl which may be substituted, OH, an alkoxy which may be substituted, an amino which may be substituted, a halogeno, a phenyl or the like; R5: H or an alkyl; R6: -COR8 (wherein R8: an alkoxy which may be substituted, a phenyloxy which may be substituted, an amino which may be substituted, or the like), -SO2R9 (wherein R9: an alkyl which may be substituted, a phenyl which may be substituted or a heterocyclyl which may be substituted), or an alkyl which may be substituted; R7: -X2R10 [wherein R10: -COR11 (where R11: OH, an alkoxy which may be substituted or an amino which may be substituted), -SO2R12 (where R12: an alkyl which may be substituted or amino which may be substituted), -N(R13)COR14 (where R13: H or an alkyl which may be substituted; R14: H or an alkyl which may be substituted), -N(R13)SO2R15 (where R13: as defined above; R15: an alkyl which may be substituted) or tetrazol-5-yl; and X2: a single bond or an alkylene which may be substituted]; X1: a methylene which may be substituted; Y1: a phenyl which may be substituted or a heterocyclyl which may be substituted; and Y2: an aryl which may be substituted, a heterocyclyl which may be substituted or the like], or the like.