51357-96-1

Basic information

• Product Name: 2-PropenaMide, N-(2-phenylethyl)-
• Synonyms: 2-PropenaMide, N-(2-phenylethyl)-
• CAS NO: 51357-96-1
• Molecular Formula: C₁₁H₁₃NO
• Molecular Weight: 175.22702
• Mol File: 51357-96-1.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-PropenaMide, N-(2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PropenaMide, N-(2-phenylethyl)-(51357-96-1)
• EPA Substance Registry System: 2-PropenaMide, N-(2-phenylethyl)-(51357-96-1)

Safety Data

• Hazardous Substances Data: 51357-96-1(Hazardous Substances Data)

Usage

Physical appearance

White to off-white crystalline solid

Primary use

Monomer in the production of polymers and copolymers for industrial applications such as adhesives, coatings, and personal care products

Other uses

Studied for potential use in drug delivery systems due to biocompatibility and ability to self-assemble into nanostructures

Potential hazards

Identified as potential allergens and irritants, caution should be taken when working with this chemical

Upstream product

• 156-28-5 2-phenylethylamine hydrochloride 
• 814-68-6 acryloyl chloride 
• 64-04-0 phenethylamine 
• 70875-36-4 N-(β-phenethyl)-3-bromopropionamide 
• 306-20-7 3-chloro-N-(4-phenylethyl)propanamide 

Downstream Products

• 70875-36-4 N-(β-phenethyl)-3-bromopropionamide 
• 1098101-09-7 (S,2E,4E)-7-methoxy-N-phenethyltetradeca-2,4-dienamide 
• 214064-41-2 17-(cyclopropylmethyl)-4,5α-epoxy-3,6β-dihydroxy-6,14-endoethenomorphinan-7α-(N-phenethyl)carboxamide 

Relevant articles and documents

The mckenna reaction – avoiding side reactions in phosphonate deprotection

The McKenna reaction is a well-known and popular method for the efficient and mild synthesis of organophosphorus acids. Bromotrimethylsilane (BTMS) is the main reagent in this reaction, which transforms dialkyl phosphonate esters into bis(trimethylsilyl)esters, which are then easily converted into the target acids. However, the versatile character of the McKenna reaction is not always used to its full extent, due to formation of side products. Herein, demonstrated by using model examples we have not only analyzed the typical side processes accompanying the McKenna reaction, but also uncovered new ones. Further, we discovered that some commonly recommended precautions did not always circumvent the side reactions. The proposed results and recommendations may facilitate the synthesis of phosphonic acids.

COMPOSITIONS AND METHODS FOR MODULATING PPP2R1A

Disclosed herein, inter alia, are compositions and methods useful for modulating PPP2R1 A and for the treatment of cancer.