51384-34-0Relevant academic research and scientific papers
Methylation of 2-Benzylideneindoline-3-one
Tomchin,Marysheva
, p. 1181 - 1185 (2007/10/03)
Methylation of 2-benzylideneindolin-3-one yields corresponding N-methyl derivative as a mixture of Z and E isomers, the former (with trans arrangement of the phenyl group with respect to carbonyl) prevailing. In addition, spirocyclic compounds are formed, previously reported 1,1″-dimethyl-3′,4′-diphenyl-dispiro[indoline-2, 1′-cyclobutane-2′,2″-indoline]-3,3″-dione and hitherto unknown 8b-methoxy-1′-methyl-2,3-diphenyl-1,2,3,8b-tetrahydrocyclopenta[b]indole- 1-spiro-2′-indolin-3′-one. Thus, a new cyclization of 2-arylmethyleneindolin-3-ones with formation of a cyclopentane ring has been revealed.
Reaction of Indol-3(2H)-one Derivatives With Some Active Methylene Compounds
Daisley, Roy W.,Elagbar, Zaha A.,Walker, John
, p. 1013 - 1016 (2007/10/02)
The reaction of substituted (Z)- and (E)-2-arylmethylideneindolin-3(2H)-ones with malononitrile gave the Michael addition products which could be cyclised to the corresponding pyranoindole.Larger molecules such as cyanoacetic acid and ethyl cyanoacetate failed to react.
