5140-38-5

Usage

Uses

Used in Pharmaceutical Industry:
Homomoschatoline is used as a bioactive compound for its potential therapeutic properties. The expression is: Homomoschatoline is used as a bioactive compound for its potential therapeutic properties due to its presence in certain plant species.
Used in Research and Development:
Homomoschatoline is used as a subject of study for further understanding its chemical properties and potential applications in various fields, including medicine and pharmacology. The expression is: Homomoschatoline is used as a subject of study for further understanding its chemical properties and potential applications in various fields.

References

Caveetal., Tetrahedron, 31,1667 (1975)

InChI:InChI=1/C19H15NO4/c1-22-17-12-8-9-20-15-13(12)14(18(23-2)19(17)24-3)10-6-4-5-7-11(10)16(15)21/h4-9H,1-3H3

Upstream product

• 3937-16-4 2-(2,3,4-trimethoxyphenyl)ethylamine 
• 118474-94-5 (E)-1-nitro-2-(2',3',4'-trimethoxyphenyl)ethene 
• 5667-97-0 5,6,7-trimethoxy-1-(2-nitro-benzyl)-3,4-dihydro-isoquinoline 
• 2103-57-3 2,3,4-trimethoxybenzaldehyde 
• 5531-84-0 N-(2,3,4-trimethoxyphenethyl)-2-(2-nitrophenyl)acetamide 
• 186581-53-3 diazomethane 
• 83375-15-9 isomoschatoline 

Relevant academic research and scientific papers

AZAFLUORENONES AND AZAANTHRAQUINONE FROM GUATTERIA DIELSIANA

Trunkwood of Guatteria dielsiana afforded eight alkaloids and one triterpene.Three of the alkaloidal constituents are oxoaporphines: liriodenine, O-methylmoschatoline and isomoschatoline; four are 1-azafluorenones: onychine, the only previously known representative of this group, and three novel compounds of this rare type, 6-methoxyonychine, dielsine (1-aza-4-methyl-2-oxo-1,2-dihydrofluorenone) and dielsinol (1-aza-4-hydroxymethyl-2-oxo-1,2-dihydrofluorenone).The last alkaloid is dielsiquinone (1-aza-3-methoxy-4-methyl-2-oxo-1,2-dihydro-9,10-anthrachenedione), the second representative of a new class of quinones of which cleistopholine was the only one previously known.The triterpene is polycarpol whose presence is of chemotaxonomic significance since this metabolite seems to be exclusive to the Annonaceae.

Novel total syntheses of oxoaporphine alkaloids enabled by mild Cu-catalyzed tandem oxidation/aromatization of 1-Bn-DHIQs

Novel total syntheses of oxoaporphine alkaloids such as liriodenine, dicentrinone, cassameridine, lysicamine, oxoglaucine and O-methylmoschatoline were developed. The key step of these total syntheses is Cu-catalyzed conversion of 1-benzyl-3,4-dihydro-isoquinolines (1-Bn-DHIQs) to 1-benzoyl-isoquinolines (1-Bz-IQs) via tandem oxidation/aromatization. This novel Cu-catalyzed conversion has been studied in detail, and was successfully used for constructing the 1-Bz-IQ core.