5667-97-0

Basic information

• Product Name: 5,6,7-trimethoxy-1-(2-nitro-benzyl)-3,4-dihydro-isoquinoline
• CAS NO: 5667-97-0
• Molecular Weight: 356.378
• Mol File: 5667-97-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5,6,7-trimethoxy-1-(2-nitro-benzyl)-3,4-dihydro-isoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6,7-trimethoxy-1-(2-nitro-benzyl)-3,4-dihydro-isoquinoline(5667-97-0)
• EPA Substance Registry System: 5,6,7-trimethoxy-1-(2-nitro-benzyl)-3,4-dihydro-isoquinoline(5667-97-0)

Safety Data

• Hazardous Substances Data: 5667-97-0(Hazardous Substances Data)

Upstream product

• 5531-84-0 N-(2,3,4-trimethoxyphenethyl)-2-(2-nitrophenyl)acetamide 
• 2103-57-3 2,3,4-trimethoxybenzaldehyde 
• 22751-23-1 (2-nitrophenyl)acetyl chloride 
• 3937-16-4 2-(2,3,4-trimethoxyphenyl)ethylamine 
• 118474-94-5 (E)-1-nitro-2-(2',3',4'-trimethoxyphenyl)ethene 
• 3740-52-1 2-(2-nitrophenyl)acetic acid 

Downstream Products

• 5140-38-5 O-methylmoschatoline 

Relevant articles and documents

Novel total syntheses of oxoaporphine alkaloids enabled by mild Cu-catalyzed tandem oxidation/aromatization of 1-Bn-DHIQs

Novel total syntheses of oxoaporphine alkaloids such as liriodenine, dicentrinone, cassameridine, lysicamine, oxoglaucine and O-methylmoschatoline were developed. The key step of these total syntheses is Cu-catalyzed conversion of 1-benzyl-3,4-dihydro-isoquinolines (1-Bn-DHIQs) to 1-benzoyl-isoquinolines (1-Bz-IQs) via tandem oxidation/aromatization. This novel Cu-catalyzed conversion has been studied in detail, and was successfully used for constructing the 1-Bz-IQ core.