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5,6,7-trimethoxy-1-(2-nitro-benzyl)-3,4-dihydro-isoquinoline is a complex organic compound belonging to the isoquinoline family. It is characterized by a 3,4-dihydro-isoquinoline core, which is a reduced form of the isoquinoline ring system. The molecule features three methoxy groups (-OCH3) attached to the 5, 6, and 7 positions of the isoquinoline nucleus, which contribute to its lipophilic properties. A 2-nitro-benzyl group (C6H4(NO2)-CH2-) is attached to the 1 position, introducing a nitro functional group that can participate in various chemical reactions. 5,6,7-trimethoxy-1-(2-nitro-benzyl)-3,4-dihydro-isoquinoline is of interest in medicinal chemistry due to its potential biological activities and may be involved in the synthesis of drugs targeting the central nervous system. Its chemical structure and properties make it a candidate for further exploration in drug development and chemical research.

5667-97-0

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5667-97-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5667-97-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,6,6 and 7 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5667-97:
(6*5)+(5*6)+(4*6)+(3*7)+(2*9)+(1*7)=130
130 % 10 = 0
So 5667-97-0 is a valid CAS Registry Number.

5667-97-0Downstream Products

5667-97-0Relevant academic research and scientific papers

Novel total syntheses of oxoaporphine alkaloids enabled by mild Cu-catalyzed tandem oxidation/aromatization of 1-Bn-DHIQs

Zheng, Bo,Qu, Hui-Ya,Meng, Tian-Zhuo,Lu, Xia,Zheng, Jie,He, Yun-Gang,Fan, Qi-Qi,Shi, Xiao-Xin

, p. 28997 - 29007 (2018/08/29)

Novel total syntheses of oxoaporphine alkaloids such as liriodenine, dicentrinone, cassameridine, lysicamine, oxoglaucine and O-methylmoschatoline were developed. The key step of these total syntheses is Cu-catalyzed conversion of 1-benzyl-3,4-dihydro-isoquinolines (1-Bn-DHIQs) to 1-benzoyl-isoquinolines (1-Bz-IQs) via tandem oxidation/aromatization. This novel Cu-catalyzed conversion has been studied in detail, and was successfully used for constructing the 1-Bz-IQ core.

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