51414-56-3

Upstream product

• 57-88-5 cholesterol 
• 76-83-5 trityl chloride 
• 57-88-5 cholesterol 
• 87839-57-4 1-(Triphenylmethyl)-4(1H)-pyridon 
• 87839-55-2 2-pyridyl trityl ether 
• 76-84-6 triphenylmethyl alcohol 

Downstream Products

• 66252-72-0 (5-Cholesten-3β-yl)-2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosid 
• 71528-63-7 cholesteryl-O-2,3,4,6-tetra-O-benzyl-β-D-mannopyranose 
• 41736-89-4 cholesteryl-O-2,3,4,6-tetra-O-benzyl-α-D-mannopyranose 
• 143520-25-6 cholesteryl 2,3,4,6-tetra-O-benzoyl-D-β-galactopyranoside 
• 41736-89-4 3-O-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)cholesterol 
• 70753-59-2 O-[2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl]cholesterol 

Relevant academic research and scientific papers

Gold(I)-catalyzed synthesis of unsymmetrical ethers using alcohols as alkylating reagents

A microwave-irradiated alcohol-protecting strategy based on gold catalysis utilizing benzyl alcohol, tert-butyl alcohol and triphenylmethanol as alkylating reagents has been developed. This protecting strategy has wide functional group tolerance with satisfactory yields for the majority of the selected alcohols. The mechanism of this transformation was probed with oxygen-18 isotope labelled alcohols assisted by GC-MS techniques and chemical kinetic experiments. This strategy provides an efficient, straightforward and alternative approach to the preparation of benzyl, tert-butyl and trityl ethers in organic synthesis.

FeCl3-catalyzed tritylation of alcohols in ionic liquids

A simple and efficient protection of alcohols as trityl ethers is described using trityl chloride in the presence of 5mol% FeCl3 as catalyst in ionic liquids at room temperature in shorter reaction times. This mild and efficient method gives access to the

Convenient method for the preparation of trityl ethers from secondary alcohols

The preparation of trityl ethers from secondary alcohols (10 mmol) with triphenylmethyl chloride (1.2 eq.) is carried out at room temperature by using DBU (1.4 eq.) as base in CH2Cl2. The high yielding procedure is very simple and it

Regioselective N- or O-Tritylation of 2(1H)-Pyridone - (Triphenylmethyl)pyridones as Tritylation Agents

Tritylation of 2(1H)-pyridone (1) with triphenylmethyl chloride (4) in acetonitrile leads exclusively to N-trityl-2(1H)-pyridone (3a) via the lithium salt 1', whereas 2-pyridyl trityl ether (3b) is the only product from the reaction with the sodium salt 1