51417-15-3

Basic information

• Product Name: 2(1H)-Pyridinone, 3-(chloromethyl)-1-methyl-
• CAS NO: 51417-15-3
• Molecular Formula: C7H8ClNO
• Molecular Weight: 157.6
• Mol File: 51417-15-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2(1H)-Pyridinone, 3-(chloromethyl)-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Pyridinone, 3-(chloromethyl)-1-methyl-(51417-15-3)
• EPA Substance Registry System: 2(1H)-Pyridinone, 3-(chloromethyl)-1-methyl-(51417-15-3)

Safety Data

• Hazardous Substances Data: 51417-15-3(Hazardous Substances Data)

Usage

Molecular Structure

2(1H)-Pyridinone, 3-(chloromethyl)-1-methylis a pyridinone derivative with a chloromethyl group attached to position 3 and a methyl group attached to position 1.

Reactivity

This chemical is highly reactive and can undergo various chemical reactions to produce a range of functionalized pyridinone derivatives.

Uses

It is used as an intermediate in the synthesis of pharmaceutical compounds, agrochemicals, and dyes.

Versatility

2(1H)-Pyridinone, 3-(chloromethyl)-1-methylis a versatile building block in the development of new drugs and other valuable chemical compounds.

Hazardous Nature

This chemical is considered potentially hazardous, and should be handled with care by trained professionals.

Upstream product

• 36721-61-6 3-(hydroxymethyl)-1-methylpyridin-2(1H)-one 
• 42463-41-2 3-(hydroxymethyl)pyridine-2(1H)-one 
• 79138-28-6 1-methyl-2-oxo-1,2-dihydropyridine-3-carbaldehyde 
• 36404-89-4 2-oxo-1,2-dihydro-pyridine-3-carbaldehyde 
• 183274-22-8 trimethylsilyl 2-(trimethylsilyloxy)nicotinate 
• 67367-27-5 methyl 1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate 
• 15506-18-0 1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid 
• 609-71-2 2-hydroxy-3-carboxypyridine 

Downstream Products

• 672939-82-1 1-methyl-3-(4-octyloxy-phenoxymethyl)-1H-pyridin-2-one 
• 672939-83-2 3-(4-dodecyloxy-phenoxymethyl)-1-methyl-1H-pyridin-2-one 
• 672939-88-7 (1R,2R,5S,6S)-3,7-Dimethyl-1,5-bis-phenoxymethyl-3,7-diaza-tricyclo[4.2.2.2^2,5]dodeca-9,11-diene-4,8-dione 
• 672939-89-8 (1R,2R,5S,6S)-3,7-Dimethyl-1,5-bis-(4-octyloxy-phenoxymethyl)-3,7-diaza-tricyclo[4.2.2.2^2,5]dodeca-9,11-diene-4,8-dione 
• 672939-90-1 (1R,2R,5S,6S)-1,5-Bis-(4-dodecyloxy-phenoxymethyl)-3,7-dimethyl-3,7-diaza-tricyclo[4.2.2.2^2,5]dodeca-9,11-diene-4,8-dione 
• 672939-80-9 1-methyl-3-phenoxymethyl-1H-pyridin-2-one 

Relevant articles and documents

MTA-Cooperative PRMT5 Inhibitors

The present invention relates to compounds that inhibit Protein Arginine N-Methyl Transferase 5 (PRMT5) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.

Photoreactivity of 2-pyridones with furan, benzene, and naphthalene. Inter- and intramolecular photocycloadditions

Pyridones, well-known for their ability to photodimerize, have been found to undergo [4 + 4] photocycloaddition with furan and naphthalene but not with benzene. In some cases these reactions can be highly regio- and stereospecific. Intramolecular reaction with furan produces both cis and trans [4 + 4] products. The cycloaddition with naphthalene can occur both inter- and intramolecularly. The intermolecular reaction yields primarily the cis isomer, whereas the trans isomer is the major product from the intramolecular reaction. A mixture of 4-methoxy-2-pyridone and 2- methoxynaphthalene that could form up to eight regio- and stereoisomers forms largely one [4 + 4] product.