36721-61-6

Basic information

• Product Name: 1-methyl-2-oxo-1,2-dihydr...
• Synonyms: 1-Methyl-2-oxo-1,2-dihydropyridine-3-Methanol;3-(hydroxymethyl)-1-methyl-1,2-dihydropyridin-2-one;3-(Hydroxymethyl)-1-methylpyridin-2(1H)-one;3-(hydroxymethyl)-1-methyl-2(1H)-Pyridinone
• CAS NO: 36721-61-6
• Molecular Formula: C₇H₉NO₂
• Molecular Weight: 139.15186
• Mol File: 36721-61-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-methyl-2-oxo-1,2-dihydr...(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-2-oxo-1,2-dihydr...(36721-61-6)
• EPA Substance Registry System: 1-methyl-2-oxo-1,2-dihydr...(36721-61-6)

Safety Data

• Hazardous Substances Data: 36721-61-6(Hazardous Substances Data)

Usage

General Description

The chemical "1-methyl-2-oxo-1,2-dihydr..." (the full chemical name was not provided) likely refers to a ketone compound with a methyl group attached to the second carbon atom. The presence of "2-oxo" in the name suggests that it contains a carbonyl group, which is a carbon atom double-bonded to an oxygen atom. The "1,2-dihydr..." portion of the name indicates that there are two hydrogen atoms attached to the first and second carbon atoms, forming a dihydric structure. 1-methyl-2-oxo-1,2-dihydr... may have various potential uses in organic synthesis, pharmaceuticals, or other chemical applications due to its specific molecular structure.

Upstream product

• 10072-09-0 3-(acetoxymethyl)pyridine 
• 77-78-1 dimethyl sulfate 
• 79138-28-6 1-methyl-2-oxo-1,2-dihydropyridine-3-carbaldehyde 
• 36404-89-4 2-oxo-1,2-dihydro-pyridine-3-carbaldehyde 
• 183274-22-8 trimethylsilyl 2-(trimethylsilyloxy)nicotinate 
• 609-71-2 2-hydroxy-3-carboxypyridine 
• 67367-27-5 methyl 1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate 
• 42463-41-2 3-(hydroxymethyl)pyridine-2(1H)-one 
• 74-88-4 methyl iodide 
• 15506-18-0 1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid 
• 100-55-0 3-hydroxymethylpyridin 

Downstream Products

• 51417-15-3 3-(chloromethyl)-1-methylpyridin-2(1H)-one 
• 267401-02-5 benzyl (3-[1-methyl-2-oxo-(1H)-pyridinyl])-methyl ether 

Relevant articles and documents

Tether-enforced reversal of regioselectivity: Head-to-head [4 + 4] photocycloaddition of 2-pyridones

Symmetric 3,3′-attachment of a three-atom chain between two pyridones overrides the head-to-tail regioselectivity found in intermolecular photodimerization reactions and gives a nearly quantitative yield of the head-to-head [4 + 4] cycloadduct containing contiguous quaternary centres.

HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME

Disclosed are compounds of formula (I): or a pharmaceutically acceptable salt thereof; wherein Y, Ra, Ra', Rc, Rf, X2, Rd, Rd', Re, Re', m, and G have the values described herein and stereochemical configurations depicted at asterisked positions indicate absolute stereochemistry, useful as inhibitors of Sumo Activating Enzyme (SAE). Further provided are pharmaceutical compositions comprising a compound of the disclosure and methods of using the compositions in the treatment of proliferative, inflammatory, cardiovascular and neurodegenerative diseases or disorders.