51419-59-1

Basic information

• Product Name: 4-Methylbenzylsulfonyl chloride
• Synonyms: (4-Methylphenyl)methanesulfonyl chloride, 4-Methylbenzenemethanesulfonyl chloride, p-Methyl-α-toluenesulfonyl chloride, p-Tolylmethanesulfonyl chloride;^a-p-Xylenesulfonyl chloride, 97%;alpha-p-Xylenesulfonyl chloride, 97%;(4-Methylphenyl)methanesulfonyl chloride, TECH;4-Methylbenzylsulfon;BenzeneMethanesulfonylchloride, 4-Methyl-;4-Methylbenzylsulfonyl chloride 96%;P-TOLYL-METHANESULFONYL CHLORIDE
• CAS NO: 51419-59-1
• Molecular Formula: C₈H₉ClO₂S
• Molecular Weight: 204.67
• Product Categories: Fluorobenzene;Phenyls & Phenyl-Het;Sulphonyl Chlorides;Phenyls & Phenyl-Het;Sulphonyl Chlorides
• Mol File: 51419-59-1.mol
• Article Data: 27

Chemical Properties

• Melting Point: 76-80 °C
• Boiling Point: 305.2 °C at 760 mmHg
• Flash Point: 138.4 °C
• Appearance: /
• Density: 1.325 g/cm³
• Vapor Pressure: 0.0015mmHg at 25°C
• Refractive Index: 1.556
• Storage Temp.: 2-8°C
• Sensitive: Moisture Sensitive
• CAS DataBase Reference: 4-Methylbenzylsulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methylbenzylsulfonyl chloride(51419-59-1)
• EPA Substance Registry System: 4-Methylbenzylsulfonyl chloride(51419-59-1)

Safety Data

• Hazard Codes: C,Xi
• Statements: 22-34
• Safety Statements: 26-28-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 51419-59-1(Hazardous Substances Data)

Usage

Uses

4-Methylbenzylsulfonyl chloride is a useful reactant for the synthesis of (R)-1-alkyl-substituted tetrahydro-ss-carbolines.

Synthesis Reference(s)

Tetrahedron Letters, 25, p. 4553, 1984 DOI: 10.1016/S0040-4039(01)81491-X

InChI:InChI=1/C8H9ClO2S/c1-7-2-4-8(5-3-7)6-12(9,10)11/h2-5H,6H2,1H3

Upstream product

• 104-82-5 4-Methylbenzyl chloride 
• 4498-99-1 4-methylbenzylthiol 
• 104-81-4 4-Methylbenzyl bromide 
• 940-63-6 amino[(4-methylbenzyl)thio]methaniminium chloride 
• 28868-76-0 2-chlorodimethylmalonate 

Downstream Products

• 78314-66-6 5-Benzyloxy-3-hydroxy-2-p-tolylmethanesulfonylamino-pentanoic acid 
• 158549-02-1 (1'R,2'S,3'R,4S,5R)-4-<5'-Methylidene-2',3'-(2-propylidenedioxy)cyclohexyl>-5-methyl-3-<(4-methylphenyl)methanesulfonyl>-2-oxazolidinone 
• 88549-89-7 (3R,3aR,4R,5R,7R,7aR)-4,5-Dihydroxy-3-((R)-1-hydroxy-ethyl)-7-phenylselanylmethyl-2-p-tolylmethanesulfonyl-octahydro-isoindol-1-one 
• 18869-29-9 (E)-4,4'-dimethylstilbene 
• 95495-85-5 cis-4,4'-dimethylstilbene episulfone 
• 1588-49-4 4,4'-dimethylstilbene 
• 126505-05-3 (E)/(Z)-Chlor-p-tolylsulfin 
• 2510-76-1 (Z)-4,4'-dimethylstilbene 
• 104-87-0 4-methyl-benzaldehyde 
• 110661-60-4 (p-methylphenyl)methanesulfonyl fluoride 
• 51392-39-3 (α-Chlor-4-methylbenzyl)(4-methylbenzyl)sulfon 
• 126423-73-2 (1'S,2'R,3'R,4S,5R)-5-<2'-Hydroxy-1'-<(4-methylphenyl)methanesulfonamido>propyl>-3,4-(2-propylidenedioxy)cyclohexanone 
• 147514-08-7 5,6-O-(2-Propylidene)-N-desalanyl-N-<(4-methylphenyl)methanesulfonyl>actinobolin 
• 147425-45-4 (1'R,2'S,3'R,4S,5R)-4-<5'-Oxo-2',3'-(2-propylidenedioxy)cyclohexyl>-5-methyl-3-<(4-methylphenyl)methanesulfonyl>-2-oxazolidinone 

Relevant articles and documents

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