126423-73-2

Upstream product

• 126423-72-1 Acetic acid (1S,2S)-2-((3aS,4S,7aS)-2,2-dimethyl-6-oxo-hexahydro-benzo[1,3]dioxol-4-yl)-1-methyl-2-p-tolylmethanesulfonylamino-ethyl ester 
• 3162-96-7 4,6-O-benzylidene-1-O-methyl-α-D-glucopyranoside 
• 147425-47-6 Methyl 3-O-benzoyl-2-O-benzyl-4,6-bis-O-(methanesulfonyl)-α-D-glucopyranoside 
• 158548-98-2 (4S,5R)-3-(tert-Butyl-dimethyl-silanyl)-4-{(S)-(tert-butyl-dimethyl-silanyloxy)-[(4S,5R)-2,2-dimethyl-5-(2-phenylsulfanylmethyl-allyl)-[1,3]dioxolan-4-yl]-methyl}-5-methyl-oxazolidin-2-one 
• 147425-42-1 (4S,5R)-3-(tert-Butyl-dimethyl-silanyl)-4-[(1S,2S,3R)-1-(tert-butyl-dimethyl-silanyloxy)-2,3-dihydroxy-5-phenylsulfanylmethyl-hex-5-enyl]-5-methyl-oxazolidin-2-one 
• 147514-07-6 Methyl 3-O-benzoyl-2-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 147425-36-3 Methyl 4-amino-3-O-benzoyl-2-O-benzyl-4,6-dideoxy-N-(ethoxycarbonyl)-α-D-galactopyranoside 
• 147425-40-9 (1'S,2'R,4S,5R)-4-<2'-(Benzyloxy)-1'-<(tert-butyldimethylsilyl)oxy>-3'-oxopropyl>-3-(tert-butyldimethylsilyl)-5-methyl-2-oxazolidinone 
• 147425-37-4 Benzoic acid (3R,4S,5S,6R)-3-benzyloxy-5-ethoxycarbonylamino-2-hydroxy-6-methyl-tetrahydro-pyran-4-yl ester 
• 147425-39-6 (1'S,2'R,4S,5R)-4-<2'-(Benzyloxy)-1'-<(tert-butyldimethylsilyl)oxy>-3'-hydroxypropyl>-3-(tert-butyldimethylsilyl)-5-methyl-2-oxazolidinone 
• 147425-48-7 Methyl 3-O-benzoyl-2-O-benzyl-6-deoxy-4-O-(methanesulfonyl)-α-D-glucopyranoside 
• 147425-35-2 Methyl 4-azido-3-O-benzoyl-2-O-benzyl-4,6-dideoxy-α-D-galactopyranoside 
• 147425-46-5 methyl 3‐O‐benzoyl‐2‐O‐benzyl‐α‐D-glucopyranoside 
• 158548-99-3 (4R,5R)-4-{(S)-[(4R,5R)-2,2-Dimethyl-5-(2-phenylsulfanylmethyl-allyl)-[1,3]dioxolan-4-yl]-hydroxy-methyl}-5-methyl-oxazolidin-2-one 

Downstream Products

• 99440-90-1 [(S)-1-((3S,4S,4aS,5S,6S)-5,6,8-Trihydroxy-3-methyl-1-oxo-3,4,4a,5,6,7-hexahydro-1H-isochromen-4-ylcarbamoyl)-ethyl]-carbamic acid benzyl ester 
• 88549-95-5 N-Cbz-actinobolin 
• 147514-08-7 5,6-O-(2-Propylidene)-N-desalanyl-N-<(4-methylphenyl)methanesulfonyl>actinobolin 
• 126423-74-3 N-((3aS,8S,9S,9aS,9bS)-5-Hydroxy-2,2,8-trimethyl-6-oxo-4,6,8,9,9a,9b-hexahydro-3aH-[1,3]dioxolo[4,5-f]isochromen-9-yl)-C-p-tolyl-methanesulfonamide 

Relevant academic research and scientific papers

Diastereoselective synthesis of actinobolin from D-glucose by application of a novel [3+3] annulation

The synthesis of 5,6-O-(2-propylidene)-N-desalanyl-N-[(4-methylphenyl)methanesulfonyl]a ctinobolin (37) is reported. The carbocyclic ring of 37 is constructed by a novel [3+3] annulation method involving sequential two-electron and one-electron allylation

The diastereoselective synthesis of (+)-actinobolin from D-glucose

The carbocyclic ring of actinobolin was constructed by a [3 + 3] annulation of a D-galactosamine derivative with 3-phenylthio-2-(trimethylsilylmethyl)propene. Formation of the lactone and acylation with L-alanine according to literature precedent gave (+)

Stereoselective total syntheses of the antitumor antibiotics (+)-actinobolin and (-)-bactobolin from a common bridged lactone intermediate

Efficient, highly steroselective approaches have been developed to (+)-actinobolin (1) and (-)-bactobolin (3) from bridged α-keto lactone 11, which can be readily prepared via intramolecular SnCl4 catalyzed ene reaction of cyclohexenol glyoxyla