51420-46-3

Basic information

• Product Name: 5-(4-morpholinyl)-1H-1,2,4-triazol-3-amine(SALTDATA: FREE)
• Synonyms: 5-(4-morpholinyl)-1H-1,2,4-triazol-3-amine(SALTDATA: FREE);5-(4-morpholinyl)-1H-1,2,4-triazol-3-amine;(5-morpholino-2H-1,2,4-triazol-3-yl)amine;3-morpholin-4-yl-1H-1,2,4-triazol-5-amine;5-morpholin-4-yl-2H-1,2,4-triazol-3-amine;5-morpholino-2H-1,2,4-triazol-3-amine;6C-029;MFCD20502878
• CAS NO: 51420-46-3
• Molecular Formula: C₆H₁₁N₅O
• Molecular Weight: 169.19
• Mol File: 51420-46-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 431.4±55.0 °C(Predicted)
• Appearance: /
• Density: 1.412±0.06 g/cm3(Predicted)
• PKA: 12.57±0.40(Predicted)
• CAS DataBase Reference: 5-(4-morpholinyl)-1H-1,2,4-triazol-3-amine(SALTDATA: FREE)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-morpholinyl)-1H-1,2,4-triazol-3-amine(SALTDATA: FREE)(51420-46-3)
• EPA Substance Registry System: 5-(4-morpholinyl)-1H-1,2,4-triazol-3-amine(SALTDATA: FREE)(51420-46-3)

Safety Data

• Hazardous Substances Data: 51420-46-3(Hazardous Substances Data)

Usage

General Description

5-(4-morpholinyl)-1H-1,2,4-triazol-3-amine, also known as SALTDATA: FREE, is a chemical compound with potential biological and pharmaceutical applications. It is a triazol-3-amine derivative containing a morpholinyl group, which makes it a potential candidate for drug development due to its ability to interact with biological targets. 5-(4-morpholinyl)-1H-1,2,4-triazol-3-amine(SALTDATA: FREE) may have therapeutic properties and is therefore of interest to researchers and pharmaceutical companies for the development of new drugs. Its chemical properties and potential biological effects make it a valuable compound for further exploration and study in the field of medicinal chemistry.

Upstream product

• 103-72-0 phenyl isothiocyanate 
• 135857-19-1 5-Amino-3-morpholin-4-yl-[1,2,4]triazole-1-carbothioic acid N-methyl-hydrazide 
• 32885-06-6 S-methyl-N''-cyano-N'-(1-cycloethoxyethyl)carbamimidothioate 

Downstream Products

• 116986-58-4 5-Amino-3-morpholin-4-yl-[1,2,4]triazole-1-carbothioic acid (3-hydroxy-phenyl)-amide 
• 116986-60-8 5-Amino-3-morpholin-4-yl-[1,2,4]triazole-1-carbothioic acid (1-phenyl-ethyl)-amide 
• 117057-03-1 5-Amino-3-morpholin-4-yl-[1,2,4]triazole-1-carbothioic acid (2,4,6-trimethyl-phenyl)-amide 
• 115549-86-5 8-benzyl-2-morpholino-6,7,8,9-tetrahydropyrido<3,4-d>-1,2,4-triazolo<1,5-a>pyrimidin-5(10H)-one 
• 121079-74-1 7,8-dihydro-2-morpholino-7-phenyl-6H-pyrrolo<3,4-d>-1,2,4-triazolo<1,5-a>pyrimidin-5(9H)-one 
• 121079-75-2 butyl 1-phenyl-4-(3-morpholino-1H-1,2,4-triazol-5-yl)imino-3-pyrrolidinecarboxylate 
• 110984-51-5 (5-Amino-3-morpholin-4-yl-[1,2,4]triazol-1-yl)-phenyl-methanone 
• 116986-42-6 5-Amino-3-morpholin-4-yl-[1,2,4]triazole-1-carboxylic acid cyclohexylamide 
• 110984-56-0 (5-Amino-3-morpholin-4-yl-[1,2,4]triazol-1-yl)-cyclohexyl-methanone 
• 110984-54-8 (5-Amino-3-morpholin-4-yl-[1,2,4]triazol-1-yl)-(3,4-dimethoxy-phenyl)-methanone 
• 113967-66-1 5-Amino-6-ethoxycarbonyl-2-morpholino-1,2,4-triazolo<1,5-a>pyrimidine 
• 110984-53-7 Acetic acid 2-(5-amino-3-morpholin-4-yl-[1,2,4]triazole-1-carbonyl)-phenyl ester 
• 110984-52-6 (5-Amino-3-morpholin-4-yl-[1,2,4]triazol-1-yl)-(4-chloro-phenyl)-methanone 
• 116986-59-5 5-Amino-3-morpholin-4-yl-[1,2,4]triazole-1-carbothioic acid benzylamide 

Relevant articles and documents

On Triazoles. XXIX. The Reaction of Triazolyl Thiohydrazides with Isocyanates and Isothiocyanates

Different N-methylsubstituted, N'-methylsubstituted and N,N'-unsubstituted triazol-1-ylcarbothiohydrazides were reacted with isocyanates and isothiocyanates to yield the corresponding carbamoyl and thiocarbamoyl derivatives 4.The thiocarbamoyl derivatives could be cyclised by heating in dimethylformamide or 10percent sodium hydroxide solution, reacting them with dicyclohexylcarbodiimide or thier alkylation to the corresponding 1,3,4-thiadiazoles 12 and 16, and derivatives 5 formed by splitting the triazole moiety.Cleaved derivatives 9 and 11 were also formed in the reaction of thiocarbamoyl derivatives 4 with carbon disulfide in the absence or presence of methyl iodide, respectively.Spectroscopic evidence is given for the structure of products obtained.