115549-75-2

Upstream product

• 51420-46-3 5-amino-3-morpholino-1H-1,2,4-triazole 
• 41276-30-6 C₉H₁₄O₃NC₆H₅ 

Downstream Products

• 126079-62-7 7,10-dibenzyl-2-morpholino-6,7,8,9-tetrahydropyrido<4,3-d><1,2,4>triazolo<1,5-a>pyrimidin-6(10H)-one 
• 115549-96-7 7-benzyl-10-(3-dimethylamino-2-methylpropyl)-2-morpholino-5,7,8,9-tetrahydropyrido<4,3-d>-1,2,4-triazolo<1,5-a>pyrimidin-6(10H)-one 
• 115549-90-1 7-benzyl-10-methyl-2-morpholino-5,7,8,9-tetrahydropyrido<4,3-d>-1,2,4-triazolo<1,5-a>pyrimidin-6(10H)-one 

Relevant academic research and scientific papers

On Triazoles XVIII. An Unexpected Rearrangement Observed During the Reaction of 5-Amino-1,2,4-triazoles with N-Heterocyclic β-Oxo-esters

In the course of the synthesis of pyrido-1,2,4-triazolopyrimidine derivatives 3c representing a novel ring system an unexpected rearrangement of the intermediate enamines to yield 5 was observed.A mechanism of the formation of 5 was suggested.The isomeric pyrido-1,2,4-triazolopyrimidine derivatives 4c containing also a new ring system were obtained, too.The structure of products obtained was proved with the help of their uv, cmr and X-ray spectra.