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1-(O3,O5-bis-trimethylsilanyl-β-D-erythro-2-deoxy-pentofuranosyl)-4-trimethylsilanyloxy-1H-pyrimidin-2-one, also known as TMS-dU-TP, is a modified nucleoside triphosphate with trimethylsilyl protecting groups. It is a versatile compound used in the synthesis and enzymatic incorporation of modified nucleotides, as well as in polymerase chain reactions (PCR). TMS-dU-TP's unique chemical composition makes it a valuable tool for studying DNA replication, repair, and other nucleic acid-related processes, and it holds potential for the development of nucleic acid-based therapeutics and diagnostics.

51432-34-9

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51432-34-9 Usage

Uses

Used in Synthesis and Enzymatic Incorporation of Modified Nucleotides:
TMS-dU-TP is used as a key intermediate for the synthesis of modified nucleotides, which are essential for various biological applications. Its role in this application is to provide a stable and functional starting material for the creation of these modified nucleotides.
Used in Polymerase Chain Reactions (PCR):
TMS-dU-TP is utilized as a component in PCR, a widely used technique for amplifying specific DNA sequences. Its presence in the reaction mixture allows for the incorporation of modified nucleotides into the amplified DNA, which can be useful for studying DNA replication and repair mechanisms.
Used in Nucleic Acid-Based Therapeutics and Diagnostics Development:
The unique chemical properties of TMS-dU-TP make it a valuable tool in the development of nucleic acid-based therapeutics and diagnostics. It can be used to create modified nucleotides that can be incorporated into DNA or RNA molecules, potentially leading to the development of new drugs and diagnostic tools for various diseases.
Used in Research Studies:
TMS-dU-TP is employed in various research studies to investigate DNA replication, repair, and other nucleic acid-related processes. Its use in these studies helps to advance our understanding of these fundamental biological processes and can contribute to the development of new treatments for diseases related to DNA and RNA dysfunction.

Check Digit Verification of cas no

The CAS Registry Mumber 51432-34-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,4,3 and 2 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 51432-34:
(7*5)+(6*1)+(5*4)+(4*3)+(3*2)+(2*3)+(1*4)=89
89 % 10 = 9
So 51432-34-9 is a valid CAS Registry Number.

51432-34-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(O3,O5-bis-trimethylsilanyl-β-D-erythro-2-deoxy-pentofuranosyl)-4-trimethylsilanyloxy-1H-pyrimidin-2-one

1.2 Other means of identification

Product number -
Other names O3',O5'-bis-trimethylsilanyl-O4-trimethylsilanyl-2'-deoxy-uridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:51432-34-9 SDS

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