51437-00-4 Usage
Chemical Properties
colorless to light yellow liqui
Uses
Different sources of media describe the Uses of 51437-00-4 differently. You can refer to the following data:
1. 5-Bromo-2-fluorotoluene is used in the preparation of 5-bromo-2-fluorobenzyl bromide via N-bromosuccinimide (NBS) bromination, required for the synthesis of crown bromofluorobenzene and 3-(4-fuoro-3-methylphenyl)acrylamide. It is also used as an intermediates of medicine.
2. 5-Bromo-2-fluorotoluene has been used in the preparation of:5-bromo-2-fluorobenzyl bromide via N-bromosuccinimide (NBS) bromination, required for the synthesis of crown bromofluorobenzene3-(4-fuoro-3-methylphenyl)acrylamide
Check Digit Verification of cas no
The CAS Registry Mumber 51437-00-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,4,3 and 7 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 51437-00:
(7*5)+(6*1)+(5*4)+(4*3)+(3*7)+(2*0)+(1*0)=94
94 % 10 = 4
So 51437-00-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H6BrF/c1-5-4-6(8)2-3-7(5)9/h2-4H,1H3
51437-00-4Relevant articles and documents
Indazoles: Regioselective protection and subsequent amine coupling reactions
Slade, David J.,Pelz, Nicholas F.,Bodnar, Wanda,Lampe, John W.,Watson, Paul S.
supporting information; experimental part, p. 6331 - 6334 (2009/12/26)
(Chemical Equation Presented) Indazoles are unselectively protected under strongly basic conditions to give a mixture at N-1 and N-2. Under mildly acidic conditions, regioselective protection at N-2 takes place. Thermodynamic conditions lead to regioselective protection at N-1. This trend applies to various substituted indazoles. Protected 5-bromoindazoles participate in Buchwald reactions with a range of amines to generate novel derivatives.
