51450-30-7

Upstream product

• 16838-89-4 2,3,5-tri-O-benzyl-D-ribofuranose 
• 160549-10-0 2,3,5-tri-O-benzyl-D-arabinofuranose 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 114762-38-8 2,3,5-tri-O-benzyl-α,β-D-ribofuranosy fluoride 
• 100-58-3 phenylmagnesium bromide 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 52554-29-7 2,3,5-tri-O-benzyl-α- and β-D-arabinofuranosyl chlorides 
• 50619-36-8 2,3,5-tri-Obenzyl-α,β-D-ribofuranosylchloride 

Relevant academic research and scientific papers

Straightforward synthesis of protected 2-hydroxyglycals by chlorination-dehydrochlorination of carbohydrate hemiacetals

A straightforward and scalable method for the synthesis of protected 2-hydroxyglycals is described. The approach is based on the chlorination of carbohydrate-derived hemiacetals, followed by an elimination reaction to establish the glycal moiety. 1,2-dehy

Simple synthesis of aromatic β-C-nucleosides via coupling of aryl grignard reagents with sugar fluorides

The perbenzylated D-ribofuranosyl fluoride is allowed to react with Grignard reagents of aromatic heterocycles such as thiophene, pyrrole, and indole in THF to afford the corresponding β-C-nucleosides in moderate yields. The present process can be also applied to perbenzylated D- glucopyranosyl fluoride and perbenzylated 2-deoxy-D-ribofuranosyl fluoride as sugar donors.