52554-29-7

Usage

Explanation

These are the chemical names of the compounds, indicating their structure and derivatives.

Explanation

They are carbon-containing molecules, which are classified as organic compounds.

Explanation

These compounds are used as building blocks in the synthesis of nucleoside analogs (molecules similar to nucleosides) and other molecules with biological activity.

Explanation

They are derived from arabinose, a naturally occurring sugar.

Explanation

They serve as reactive intermediates, which are temporary products in a chemical reaction, used to form the final product.

Explanation

The presence of the benzyl group increases the reactivity of the compound, making it more useful in various chemical transformations.

Explanation

These compounds have been studied for their potential to exhibit anti-cancer and antiviral properties, which could be useful in the development of pharmaceuticals.

Explanation

They are used in the preparation of various pharmaceuticals and serve as valuable tools in both academic and industrial research settings.

Explanation

These compounds are useful in the synthesis of complex molecules, making them valuable reagents in organic chemistry.

Type

Organic compounds

Synthesis use

Nucleoside analogs and bioactive molecules

Derivative of

Arabinose

Role

Reactive intermediates in organic chemistry

Benzyl group attachment

Enhanced reactivity

Potential properties

Anti-cancer and antiviral

Applications

Pharmaceutical preparation, academic and industrial research

Complexity

Synthesis of complex molecules

Upstream product

• 62255-44-1 1-O-acetyl-2,3,5-tris-O-(benzyl)-α, β-D-arabinofuranose 
• 160549-10-0 2,3,5-tri-O-benzyl-D-arabinofuranose 
• 31598-79-5 2,3,5-tri-O-benzyl-1-O-(p-nitrobenzoyl)-α-D-arabinofuranose 

Downstream Products

• 133636-73-4 4,6-dichloro-1-(2,3,5-tri-O-benzyl-β-D-arabinofuranosyl)-1H-pyrrolo<3,2-c>pyridine 
• 133636-74-5 4,6-dichloro-1-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)-1H-pyrrolo<3,2-c>pyridine 
• 142372-15-4 2,5,6-Trichloro-1-(2,3,5-tri-O-benzyl-β-D-arabinofuranosyl)benzimidazole 
• 1402833-58-2 S-acetyl-2,3,5-tris-O-(benzyl)-1-thio-β-D-arabinofuranose 
• 51450-30-7 1,4-anhydro-2,3,5-tri-O-benzyl-D-erythro-pent-1-enitol 
• 40491-00-7 1-(tri-O-benzyl-β-D-arabinofuranosyl)-1H-[1,2,4]triazole-3-carboxylic acid amide 
• 129468-43-5 1-(2,3,5-tri-O-benzyl-β-D-arabinofuranosyl)-1H-pyrazolo<3.4-d>pyrimidin-4-one 
• 129491-72-1 2-(2,3,5-tri-O-benzyl-β-D-arabinofuranosyl)-21H-pyrazolo<3.4-d>pyrimidin-4-one 
• 129468-46-8 4-amino-2-(2,3,5-tri-O-benzyl-β-D-arabinofuranosyl)-2H-pyrazolo<3.4-d>pyrimidine 
• 129468-40-2 1-(2,3-O-dibenzyl-β-D-arabinofuranosyl)-4-methoxy-1H-pyrazolo<3.4-d>pyrimidine 
• 133636-75-6 1-(β-D-arabinofuranosyl)-3-benzyl-4,6-dichloro-1H-pyrrolo<3,2-c>pyridine 
• 129468-41-3 1-(2-O-benzyl-β-D-arabinofuranosyl)-4-methoxy-1H-pyrazolo<3.4-d>pyrimidine 
• 76054-93-8 5-Amino-1-((3S,4R,5R)-3,4-bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-1H-imidazole-4-carboxylic acid amide 
• 80161-97-3 4-amino-6-chloro-1-(2,3,5-tri-O-benzyl-β-D-arabinofuranosyl)imidazo<4,5-c>pyridine 

Relevant academic research and scientific papers

β-D-Arabinosyl 1- C -sulfonic acid

A short synthetic route to β,D-arabinofuranosyl 1-C-sulfonic acid (7), a possible biomimetic for the arabinofuranosyl anomeric phosphate, is described. The furanosyl 1-C-sulfonate was prepared by buffered dimethyldioxirane oxidation of an S-acetyl-1-thio-

Stereoselective synthesis of 9-β-d-arabianofuranosyl guanine and 2-amino-9-(β-d-arabianofuranosyl)purine

9-β-d-Arabianofuranosyl guanine (6) and 2-amino-9-(β-d- arabianofuranosyl)purine (8) were prepared from 2-amino-6-chloro-9-(2,3,5- triphenylmethoxyl-β-d-arabianofuranosyl)purine (4), a key intermediate which was stereoselectively prepared from 2,3,5-triphenylmethoxyl-d- arabianofuranose and 2-amino-6-chloro-purine. The yield of the intermediate was obviously improved and only β-isomer was formed by using the activated molecular sieve as environmental friendly catalyst, overcoming the defect that a 1:1 mixture of α- and β-isomers was formed, which was difficult to separate, when toxic mercury cyanide was previously used as catalyst.

A convenient synthesis of glycosyl chlorides from sugar hemiacetals using triphosgene as the chlorine source

Treating partially protected sugar hemiacetals with triphosgene in THF results in the formation of glycosyl chlorides. The method is compatible with acid-sensitive isopropylidene protecting groups in the hemiacetal substrates. (C) 2000 Elsevier Science Lt

Synthesis of Allopurinol and 4-Amino-1H-pyrazolopyrimidine N1- and N2-(β-D-Arabinofuranosides)

Allopurinol and 4-amino-1H-pyrazolopyrimidine N1- and N2-(D-arabinofuranosides) have been synthesized.Nucleobase anion glycosylation of 4-methoxy-1H-pyrazolopyrimidine (7) with the α-D-arabinofuranosyl chloride 6a proce