51454-63-8

Basic information

• Product Name: 4-CYANO-PYRIDINE-2-METHANOL
• Synonyms: 4-CYANO-PYRIDINE-2-METHANOL;2-HYDROXYMETHYL-ISONICOTINONITRILE;4-CYNO-PYRIDINE-2-METHANOL;4-Cyano-2-(hydroxymethyl)pyridine;2-(hydroxyMethyl)-4-Pyridinecarbonitrile;2-(hydroxymethyl)pyridine-4-carbonitrile
• CAS NO: 51454-63-8
• Molecular Formula: C₇H₆N₂O
• Molecular Weight: 134.14
• Mol File: 51454-63-8.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 282.4 °C at 760 mmHg
• Flash Point: 124.6 °C
• Appearance: /
• Density: 1.25 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.06±0.10(Predicted)
• CAS DataBase Reference: 4-CYANO-PYRIDINE-2-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CYANO-PYRIDINE-2-METHANOL(51454-63-8)
• EPA Substance Registry System: 4-CYANO-PYRIDINE-2-METHANOL(51454-63-8)

Safety Data

• Hazardous Substances Data: 51454-63-8(Hazardous Substances Data)

Usage

Description

4-Cyano-pyridine-2-methanol, also known as 2-cyano-isonicotinic acid, is a chemical compound with the molecular formula C7H6N2O. It is a white to off-white crystalline powder that serves as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals, particularly those targeting the central nervous system and cardiovascular system.

Uses

Used in Pharmaceutical Industry:
4-Cyano-pyridine-2-methanol is used as a key intermediate for the synthesis of various drugs, especially those that act on the central nervous system and cardiovascular system. Its unique chemical structure allows for the development of medications with specific therapeutic effects.
Used in Agrochemical Industry:
4-Cyano-pyridine-2-methanol is used as a building block in the manufacture of herbicides and insecticides. Its incorporation into these products enhances their effectiveness in controlling weeds and pests, contributing to improved agricultural yields and crop protection.

Upstream product

• 100-48-1 pyridine-4-carbonitrile 
• 7285-11-2 chloroform methanol 
• 7664-93-9 sulfuric acid 
• 2950-43-8 hydroxylamine-O-sulfonic acid 
• 30342-68-8 N-Ethoxy-2-picolinium iodide 
• 98549-84-9 4-Cyano-2-picoline-N-oxide 
• 2214-53-1 2-methyl-4-cyanopyridine 
• 931-19-1 2-methylpyridine N-oxide 
• 14906-59-3 4-cyanopyridine N-oxide 
• 51454-62-7 2-acetoxymethyl-isonicotinonitrile 
• 67-56-1 methanol 

Downstream Products

• 1201446-41-4 N₁-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)pyridin-2-yl)methyl)-N₂,N₂-diethylethane-1,2-diamine 
• 1201446-08-3 (4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)pyridin-2-yl)methanol 
• 1201448-11-4 C₁₈H₁₇N₃O₄ 
• 106474-82-2 4-cyano-2-(2-hydroxy)-ethylpyridine 
• 185220-30-8 2-(1'-hydroxyethyl)-4-acetylpyridine 
• 597563-02-5 2-(bromomethyl)isonicotinonitrile 
• 116308-38-4 4-Cyano-2-pyridinecarboxaldehyde 
• 108337-75-3 2-(N-Benzyl-N-methylamino)ethyl Methyl 4-(4-Cyano-2-pyridyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 

Relevant articles and documents

KCNT1 INHIBITORS AND METHODS OF USE

The present invention is directed to, in part, compounds and compositions useful for preventing and/or treating a neurological disease or disorder, a disease or condition relating to excessive neuronal excitability, and/or a gain-of-function mutation in a gene (e.g., KCNT1). Methods of treating a neurological disease or disorder, a disease or condition relating to excessive neuronal excitability, and/or a gain-of-function mutation in a gene such as KCNT1 are also provided herein.

AROMATIC RING COMPOUND

Provided is an aromatic ring compound having a GPR40 agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof has a GPR40 agonist activity, and is useful as an agent for the prophylaxis or treatment of diabetes and the like.

POTENTIATORS OF GLUTAMATE RECEPTORS

The present invention provides compounds of formula (I); pharmaceutical compositions thereof, and methods of using the same, processes or preparing the same, and intermediates thereof.