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51454-63-8 Usage

General Description

4-Cyano-pyridine-2-methanol, also known as 2-cyano-isonicotinic acid, is a chemical compound with the molecular formula C7H6N2O. It is a white to off-white crystalline powder that is used in the production of pharmaceuticals and agrochemicals. 4-CYANO-PYRIDINE-2-METHANOL is a key intermediate in the synthesis of various drugs, especially those that act on the central nervous system and cardiovascular system. It is also used as a building block in the manufacture of herbicides and insecticides. 4-Cyano-pyridine-2-methanol is an important chemical in the pharmaceutical and agrochemical industries, playing a crucial role in the development and production of various medicinal and agricultural products.

Check Digit Verification of cas no

The CAS Registry Mumber 51454-63-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,4,5 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 51454-63:
108 % 10 = 8
So 51454-63-8 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017


1.1 GHS Product identifier

Product name 2-(hydroxymethyl)pyridine-4-carbonitrile

1.2 Other means of identification

Product number -
Other names 2-(Hydroxymethyl)isonicotinonitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:51454-63-8 SDS

51454-63-8Relevant articles and documents



Paragraph 000853, (2020/11/23)

The present invention is directed to, in part, compounds and compositions useful for preventing and/or treating a neurological disease or disorder, a disease or condition relating to excessive neuronal excitability, and/or a gain-of-function mutation in a gene (e.g., KCNT1). Methods of treating a neurological disease or disorder, a disease or condition relating to excessive neuronal excitability, and/or a gain-of-function mutation in a gene such as KCNT1 are also provided herein.



Paragraph 0406, (2015/01/18)

Provided is an aromatic ring compound having a GPR40 agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof has a GPR40 agonist activity, and is useful as an agent for the prophylaxis or treatment of diabetes and the like.



Page/Page column 46-47, (2008/06/13)

A compound of formula (I): for use in treating cancer or other diseases ameliorated by the inhibition of PARP, wherein: A and B together represent an optionally substituted, fused aromatic ring; X can be NRx or CRxRy; if X=NRx then n is 1 or 2 and if X=CRxRy then n is 1; Rx is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; Ry is selected from H, hydroxy, amino; or Rx and Ry may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; RC1 and RC2 are independently selected from the group consisting of hydrogen and C1-4 alkyl, or when X is CRxRy, RC1, RC2, Rx and Ry, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; R1 is selected from H and halo; and Het is selected from: (i) formula (i), where Y1 is selected from CH and N, Y2 is selected from CH and N, Y3 is selected from CH, CF and N, where only one or two of Y1, Y2 and Y3 can be N; and (ii) formula (ii), where Q is O or S.

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