5149-74-6Relevant academic research and scientific papers
Studies of the reaction between indole-2,3-diones (isatins) and secondary aliphatic amines
Bergman, Jan,Stalhandske, Claes,Vallberg, Hans
, p. 753 - 759 (2007/10/03)
Simple secondary aliphatic amines react with isatin to yield, depending on the structure, either 2-amino-phenylglyoxamides, such as 2-amino-N,N-dimethylphenylglyoxamide, or dialkylammonium salts of 2-aminophenylglyoxylic acids. Reaction of isatin with N,N′-dimethylethylenediamine gave an unusual 2:1 product, whose structure has been determined by X-ray crystallography. Acta Chemica Scandinavica 1997.
