78662-38-1Relevant academic research and scientific papers
Leucine rich repeat kinase 2 (LRRK2) inhibitors based on indolinone scaffold: Potential pro-neurogenic agents
Salado, Irene G.,Zaldivar-Diez, Josefa,Sebastian, Victor,Li, Lingling,Geiger, Larissa,González, Silvia,Campillo, Nuria E.,Gil, Carmen,Morales, Aixa V.,Perez, Daniel I.,Martinez, Ana
, p. 328 - 342 (2017/07/07)
Leucine-rich repeat kinase 2 (LRRK2) is one of the most pursued targets for Parkinson's disease (PD) therapy. Moreover, it has recently described its role in regulating Wnt signaling and thus, it may be involved in adult neurogenesis. This new hypothesis
Remote activation of the nucleophilicity of isatin
Zari, Sergei,Kudrjashova, Marina,Pehk, Tonis,Lopp, Margus,Kanger, Tonis
supporting information, p. 1740 - 1743 (2014/04/17)
The concept of the remote activation of reactivity was first applied in asymmetric organocatalysis. An isatin 3-phenylimine derivative acts as a donor in the thiourea catalyzed asymmetric addition to unsaturated 1,4-ketoesters, affording aza-Michael adducts in high enantiomeric purity and yield.
Some isatin Schiff bases as corrosion inhibitors for iron in sulphuric acid solution
Mohamed, A. K.,Bekheit, M. M.,Fouda, A. S.
, p. 331 - 336 (2007/10/02)
Six isatin Schiff bases have been prepared and treated as inhibitors for the corrosion of iron in 1 mol L-1 sulphuric acid.The inhibitor efficiencies calculated from weight loss and polarization methods are in good agreement.The Tafel slope is
