515-82-2

Usage

Uses

Used in Pesticide and Herbicide Industries:
N-(2,2,2-trichloro-1-hydroxyethyl)formamide is used as a chemical intermediate for the synthesis of various pesticides and herbicides. Its role in these applications is crucial for the development of effective products that control, repel, or kill unwanted plants and insects, thereby protecting crops and enhancing agricultural productivity.
However, it is important to note that due to its potential toxicity and environmental impact, the use of N-(2,2,2-trichloro-1-hydroxyethyl)formamide must be carefully managed and regulated to minimize any adverse effects on ecosystems and human health.

InChI:InChI=1/C3H4Cl3NO2/c4-3(5,6)2(9)7-1-8/h1-2,9H,(H,7,8)

Upstream product

• 77287-34-4 formamide 
• 75-87-6 chloral 

Downstream Products

• 5816-02-4 10,10'-(1,2-ethanediylidene)bisanthrone 
• 3659-66-3 1,2,2,2-tetrachloro-1-formamidoethane 
• 136861-87-5 2-(4-Chloro-3-fluorophenyl)-5-(4-propylphenyl)-pyridine 

Relevant academic research and scientific papers

THE CRYSTAL AND ELECTRON STRUCTURE OF N-(2,2,2-TRICHLORO-1-MORPHOLINO-ETHYL) FORMAMIDE

The crystal structure was solved by direct methods and refined by the least squares method in a 9 x 9 block diagonal approximation using the anisotropic temperature parameters.The R-factor was decreased to a final value of 5.6percent for 970 observed reflextions.The crystal are monoclinic with a space group of P21/c and lattice parameters of a = 1.1056(11), b = 0.8913(11), c = 1.2023(16) nm, β = 96.32, and Z = 4.The crystal structure consists of discrete molecules between which hydrogen interactions of the N-HO and C-HO type were observed.The lengths of the N1-C3 (0.1432 nm) and C3-O1 (0.1203 nm) bonds and valence angles, C3-N1-C1 (119.9), N1-C3-O1 (126.5), indicate considerable delocalization of the ?-electrons and participation of the lone electrone pair on N1 nitrogen in the conjugation in the N1-C3-O1 molecular fragment.The CNDO/2 quantum chemical method was used to calculate the electron structure.Calculation for partial optimization of the dihedral angles, φ and ω, indicated that the most stable form is obtained for the values φ = 0, ψ = 120-150, 240-270 and ω = 150-210,330-30.

Process for the preparation of isocyanate derivatives of aliphatic, cycloaliphatic, and araliphatic compounds

A process for the preparation of derivatives of aliphatic, cycloaliphatic, and araliphatic compounds containing from 1 to 3 isocyanate groups bonded to from 1 to 3 secondary or tertiary carbon atoms, or a combination thereof, is disclosed. The process comprises reacting a compound of the formula R--(CO--NHCl)n, wherein R represents an aliphatic, cycloaliphatic, or araliphatic radical, with a tertiary amine having a pKa greater than 7, at a temperature from about 20° to about 180° C., in an inert solvent, to form a compound of the formula R--(N=C=O)n, wherein the isocyanate groups are bonded to secondary or tertiary carbon atoms.