51504-52-0

Basic information

• Product Name: 6-(acetylamino)-N,N-dimethylhexanamide
• Synonyms: hexanamide, 6-(acetylamino)-N,N-dimethyl-
• CAS NO: 51504-52-0
• Molecular Formula: C₁₀H₂₀N₂O₂
• Molecular Weight: 200.278
• Mol File: 51504-52-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 390.4°C at 760 mmHg
• Flash Point: 189.9°C
• Density: 0.982g/cm³
• Vapor Pressure: 2.66E-06mmHg at 25°C
• Refractive Index: 1.459
• CAS DataBase Reference: 6-(acetylamino)-N,N-dimethylhexanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(acetylamino)-N,N-dimethylhexanamide(51504-52-0)
• EPA Substance Registry System: 6-(acetylamino)-N,N-dimethylhexanamide(51504-52-0)

Safety Data

• Hazardous Substances Data: 51504-52-0(Hazardous Substances Data)

Upstream product

• 32039-13-7 methyl 6-acetamidohexanoate 
• 124-40-3 dimethyl amine 

Relevant articles and documents

Chemical differentiating agents. Differentiation of HL-60 cells by hexamethylenebis[acetamide] analogues

Hexamethylenebis[acetamide] (HMBA) is an agent in clinical trial that induces differentiation of certain types of tumor cells to nonmalignant phenotypes. In an attempt to discover a more potent compound, a number of bis-functionalized amides, imides, and hydrazine derivatives of HMBA were prepared and evaluated in vitro with the HL-60 human promyelocytic leukemia cell line. Among the compounds evaluated, the 5,5-dimethylhydantoin derivative is almost 10 times more potent than HMBA in inducing differentiation. The bis-imide, diacetyl-HMBA is both more potent and effective than its parent compound. Six of the 16 compounds evaluated cause at least 20% differentiation. An inverse relationship between the degree of differentiation and the percentage of viable cells is described for HMBA and its analogues.