515138-35-9

Upstream product

• 515138-49-5 6-acetamido-3,5-dimethyl-1,2-benzisoxazole 
• 726174-61-4 5-chloromethyl-4-isopropyl-2-[4-(trifluoromethyl)phenyl]thiazole 
• 591774-94-6 methyl 4-isopropyl-2-[4-(trifluoromethyl) phenyl]thiazole-5-carboxylate 
• 592519-45-4 4-isopropyl-2-[4-(trifluoromethyl)phenyl]thiazole-5-methanol 
• 42558-54-3 Methyl 4-methyl-3-oxopentanoate 
• 72505-21-6 4-trifluoromethylbenzthioamide 

Downstream Products

• 515138-36-0 6-amino-3-[2-[4-isopropyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]ethyl]-5-methyl-1,2-benzisoxazole 
• 515138-37-1 6-hydroxy-3-[2-[4-isopropyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]ethyl]-5-methyl-1,2-benzisoxazole 

Relevant academic research and scientific papers

Biological evaluation of novel benzisoxazole derivatives as PPARδ agonists

We discovered novel peroxisome proliferator-activated receptor δ agonists with a characteristic benzisoxazole ring. Compound 5 exhibited potent human PPARδ transactivation activity. Furthermore, it stimulated the differentiation of oligodendrocyte precurs