515143-18-7

Upstream product

• 67-56-1 methanol 
• 5707-04-0 Phenylselenyl chloride 
• 515143-08-5 3-[(1S,2R)-2-methoxy-1-apocamphane-1-carbonyl]-2-thiazolone 
• 139174-14-4 (1S,2R)-7,7-dimethyl-2-methoxybicyclo[2.2.1]heptane-1-carboxylic acid chloride 
• 125554-29-2 (1S,2R)-2-methoxy-1-apocamphane-1-carboxylic acid 

Relevant academic research and scientific papers

Chiral functionalization of 2(3H)-thiazolone. New route to chiral synthons for 2-amino thiols

Treatment of 3-[2(R)-methoxyethoxy- or 3-[2(R)-methoxyethoxyethoxy-7,7-dimethylbicyclo[2.2.1] heptane-1(S)-carbonyl]-2-thiazolones with Br2 / MeC(OMe)3 and C6H5SeCl / MeOH resulted in the diastereoselective formation of 4(S)-methoxy-5(S)-bromo- and 4(R)-methoxy-5(R)-phenylseleno-2-thiazolidinones, respectively, with high to excellent π-facial selectivity, but with opposite diastereofacial selection. The adducts thus obtained are potentially useful as chiral synthons for 2-amino thiols.