515157-47-8Relevant academic research and scientific papers
Borinic Acids via Direct Arylation of Amine-Borane Complexes: An Air- and Water-Stable Boron Source
Richard, Jimmy,Birepinte, Mélodie,Charbonnier, Jean Baptiste,Liautard, Virginie,Pinet, Sandra,Pucheault, Mathieu
, p. 736 - 744 (2017/02/15)
A synthesis of borinic acids and borinates was optimized using amine-borane complexes as a water and air insensitive borylating agent. The reaction operates under convenient conditions using a non-cryogenic temperature and with no flash chromatography, and it gives no boron impurities. The reaction proceeds through a tandem dehydrogenation-double addition mechanism.
Synthesis of Borinic Acids and Borinate Adducts Using Diisopropylaminoborane
Marciasini, Ludovic,Cacciuttolo, Bastien,Vaultier, Michel,Pucheault, Mathieu
supporting information, p. 3532 - 3535 (2015/07/28)
In situ formation of aryl Grignard under Barbier condition and diisopropylaminoborane as boron source allows a complete control of the addition onto the boron electrophile. Analytically pure borinic acid derivatives were produced at the gram scale without column chromatography and isolated as borinates adducts, with ethanolamine or 8-hydroxyquinoline, after workup.
PROCESS FOR MANUFACTURING PICOLINATE BORINIC ESTERS
-
Page/Page column 14, (2008/06/13)
The present invention relates to the field of boron-containing compounds, particularly boron compounds and pharmaceutical compositions thereof that exhibit with antibacterial and/or anti-inflammatory activities, and uses thereof. Methods for preparing and
Identification of a novel boron-containing antibacterial agent (AN0128) with anti-inflammatory activity, for the potential treatment of cutaneous diseases
Baker, Stephen J.,Akama, Tsutomu,Zhang, Yong-Kang,Sauro, Vittorio,Pandit, Chetan,Singh, Rajeshwar,Kully, Maureen,Khan, Jehangir,Plattner, Jacob J.,Benkovic, Stephen J.,Lee, Ving,Maples, Kirk R.
, p. 5963 - 5967 (2007/10/03)
A series of borinic acid picolinate esters were synthesized and screened for their minimum inhibitory concentration (MIC) against Gram-positive and -negative bacteria. Our lead compounds were then screened for anti-inflammatory activity. From these studie
Antibiotics containing borinic acid complexes and methods of use
-
, (2008/06/13)
The structure and preparation of antibiotics incorporating borinic acid complexes are disclosed, especially hydroxyquinoline, imidazole and picolinic acid derivatives, along with compositions of these antibiotics and methods of using the antibiotics and compositions as bactericidal and fungicidal agents as well as therapeutic agents for the treatment of diseases caused by bacteria and fungi.
BORON-CONTAINING COMPOUNDS AND METHODS OF USE
-
Page/Page column 38, (2010/02/15)
Methods of treating and/or preventing surface infections, such as acne, in an animal, such as a human being, using antibiotics incorporating borinic acid complexes, especially picolinic acid derivatives, are disclosed, along with compositions of these ant
INTRACELLULAR CALCIUM CONCENTRATION INCREASE INHIBITORS
-
Page/Page column 28-29, (2010/02/07)
An intracellular calcium concentration increase inhibitor containing as the active ingredient (1) a boron compound represented by the formula (I). The compound represented by the formula (I) inhibits the increase of the intracellular calcium concentration
