83846-48-4

Basic information

• Product Name: 2-CHLORO-4-IODOTOLUENE
• Synonyms: 2-CHLORO-4-IODO-1-METHYLBENZENE;2-CHLORO-4-IODOTOLUENE;2-Chloro-4-iodotoluene, 98+%;1-Methyl-2-chloro-4-iodobenzene;281-024-0;2-Chloro-4-iodotoluene, stabilized with copper
• CAS NO: 83846-48-4
• Molecular Formula: C₇H₆ClI
• Molecular Weight: 252.48
• EINECS: 281-024-0
• Product Categories: Aromatic Hydrocarbons (substituted) & Derivatives;Halogen toluene;Chlorine Compounds;Iodine Compounds
• Mol File: 83846-48-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 22 °C
• Boiling Point: 118 °C
• Flash Point: 145°C/35mm
• Appearance: Yellowish oily liquid
• Density: 1,8 g/cm3
• Vapor Pressure: 0.0568mmHg at 25°C
• Refractive Index: 1.6211
• Storage Temp.: Room temperature.
• Sensitive: Light Sensitive
• BRN: 3234854
• CAS DataBase Reference: 2-CHLORO-4-IODOTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-4-IODOTOLUENE(83846-48-4)
• EPA Substance Registry System: 2-CHLORO-4-IODOTOLUENE(83846-48-4)

Safety Data

• Hazard Codes: Xi,N
• Statements: 36/37/38-51/53-41-37/38
• Safety Statements: 26-36/37/39-37/39-61-39-60-37-23
• HazardClass: IRRITANT
• Hazardous Substances Data: 83846-48-4(Hazardous Substances Data)

Usage

Uses

It finds its application in the identification of a novel boron-containing antibacterial agent (AN0128) with anti-inflammatory activity, for the potential treatment of cutaneous diseases.

InChI:InChI=1/C7H6ClI/c1-5-2-3-6(9)4-7(5)8/h2-4H,1H3

Upstream product

• 591-50-4 iodobenzene 
• 95-49-8 2-methylchlorobenzene 
• 95-74-9 3-chloro-p-toluidine 

Downstream Products

• 515157-47-8 B,B-bis(3-chloro-4-methylphenyl)borinic acid 
• 19482-08-7 3-chloro-4-methyl-1,1'-biphenyl 
• 208335-68-6 3-(3-chloro-4-methylphenyl)-N-methylpropiolamide 
• 1208119-67-8 2‐chloro‐4‐(2‐cyclopropylethynyl)‐1‐methylbenzene 
• 890316-56-0 tert-butyl 2-(benzamido)-4-(3-chloro-4-methylphenyl)benzoate 
• 74483-47-9 2-Chloro-4-(trifluoromethyl)toluene 
• 135049-84-2 4-bromomethyl-3-chloroiodobenzene 
• 219767-53-0 2-(3-chloro-4-methylphenyl)thiophene 
• 872044-70-7 3-hydroxypyridine-2-carbonyloxy-bis(3-chloro-4-methylphenyl)borane 
• 428854-77-7 (1S,3S,6R,10S)-(Z)-9-(3-chloro-4-methylbenzylidene)-7-azatricyclo[4.3.1.0^3,7]decane-10-carboxylic acid methyl ester 
• 808744-19-6 2-(3-chloro-4-methylphenyl)-1,3-oxazole 

Relevant articles and documents

A simple and efficient iodination of aromatic compounds using I2/Choline Chloride/K2S2O8

A simple and efficient method for the iodination of aromatic compounds has been achieved in the presence of molecular iodine, choline chloride and potassium peroxodisulfate at 65 °C in acetonitrile. The rate of conversion of aromatic compounds into iodoaromatic compounds was promoted by in situ formed choline peroxodisulfate. This protocol provides an efficient access to iodoarenes with operational simplicity, good functional group tolerance and a moderate to good product yield.

METHOD OF PRODUCING IODIZING AGENT, AND METHOD OF PRODUCING AROMATIC IODINE COMPOUND

A method of the present invention, for producing an iodizing agent, includes the step of electrolyzing iodine molecules in a solution by using an acid as a supporting electrolyte. This realizes (i) a method of producing an iodine cation suitable for use as an iodizing agent that does not require a sophisticated separation operation after iodizing reaction is completed, and (ii) an electrolyte used in the method. Further, a method of the present invention, for producing an aromatic iodine compound, includes the step of causing an iodizing agent, and an aromatic compound whose nucleus has one or more substituent groups and two or more hydrogen atoms, to react with each other under the presence of a certain ether compound. This realizes such a method of producing an aromatic iodine compound that position selectivity in iodizing reaction of an aromatic compound is improved.