515160-09-5Relevant articles and documents
Application of Baylis-Hillman methodology in the synthesis of coumarin derivatives
Kaye, Perry T.,Musa
, p. 1755 - 1770 (2007/10/03)
A general, chemoselective approach to 3-substituted coumarins via Baylis-Hillman reactions of O-benzylated salicylaldehyde precursors has been demonstrated. Competitive cyclization to chromene derivatives is inhibited by conjugate addition of benzylamine or piperidine to the α,β-unsaturated ester intermediates.