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2-Methoxyethane-1-sulfonaMide, also known as MESNA, is a synthetic organic compound with the chemical formula C6H13NO3S. It is primarily used as a detoxifying agent in the treatment of chemotherapy-induced hemorrhagic cystitis and in the management of paracetamol overdoses.

51517-04-5

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51517-04-5 Usage

Uses

Used in Pharmaceutical Industry:
2-Methoxyethane-1-sulfonaMide is used as a detoxifying agent for the treatment of chemotherapy-induced hemorrhagic cystitis and paracetamol overdoses. It works by binding to and inactivating toxic metabolites of chemotherapy drugs, such as ifosfamide, and preventing damage to the bladder wall.
Used in Medical Industry:
2-Methoxyethane-1-sulfonaMide is used as a mucolytic agent and is sometimes used as a stabilizer for certain medications. It is administered intravenously or orally and is generally well tolerated with minimal side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 51517-04-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,5,1 and 7 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 51517-04:
(7*5)+(6*1)+(5*5)+(4*1)+(3*7)+(2*0)+(1*4)=95
95 % 10 = 5
So 51517-04-5 is a valid CAS Registry Number.

51517-04-5Relevant academic research and scientific papers

THIAZOLIDINONE COMPOUNDS AND USE THEREOF

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Paragraph 1250-1251, (2017/09/21)

A pharmaceutical composition containing a compound of Formula (I) for treating an opioid receptor-associated condition. Also disclosed is a method for treating an opioid receptor-associated condition using such a compound. Further disclosed are two sets of thiazolidinone compounds of formula (I): (i) compounds each having an enantiomeric excess greater than 90% and (ii) compounds each being substituted with deuterium.

NITROGENATED HETEROCYCLIC COMPOUND

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Paragraph 0093, (2014/11/27)

A nitrogen-containing heterocyclic compound represented by formula (I-A): (wherein R1A represents lower alkyl which may be substituted with lower alkoxy, R3A represents lower alkyl substituted with fluorine atom(s), and RqA represents an optionally substituted aromatic heterocyclic group) or the like, or a pharmaceutically acceptable salt thereof; and the like, are provided.

NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING INHIBITORY EFFECT ON PRODUCTION OF KYNURENINE

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Paragraph 0234, (2013/03/28)

The present invention provides a nitrogen-containing heterocyclic compound or a pharmaceutically acceptable salt thereof having an inhibitory effect on the production of kynurenine, represented by formula (I): (wherein R6 and R7 may be the same or different and each represent a hydrogen atom or the like, R8, R9, R19, and R11 may be the same or different and each represent a hydrogen atom or the like, R1 represents lower alkyl which may be substituted with cycloalkyl, or the like, and R3 represents optionally substituted aryl or an optionally substituted heterocyclic group).

N - ( 2 - aryl - propionyl ) - sulfonamides and pharmaceutical preparations containing them

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, (2008/06/13)

The compounds of formula 1, wherein R and R2 are as defined in the disclosure, are useful in the prevention and treatment of tissue damage due to exacerbated recruitment of polymorphonuclear neutrophils (PMN leukocytes) at the inflammatory sites.

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