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Product FOB Price Min.Order Supply Ability Supplier
(R)-2-Flurbiprofen Manufacturer/High quality/Best price/In stock
Cas No: 51543-40-9
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
High quality (R)-2-Flurbiprofenr supplier in China
Cas No: 51543-40-9
No Data No Data 30 Metric Ton/Month Simagchem Corporation Contact Supplier
Factory Price API 99% (R)-2-Flurbiprofen 51543-40-9 GMP Manufacturer
Cas No: 51543-40-9
USD $ 0.1-0.1 / Gram 1 Gram 100 Metric Ton/Year Xi'an Xszo Chem Co., Ltd. Contact Supplier
(2R)-2-(3-fluoro-4-phenyl-phenyl)propanoic acid
Cas No: 51543-40-9
USD $ 1.0-1.0 / Kilogram 1 Kilogram 2000 Metric Ton/Year Henan Sinotech Import&Export Corporation Contact Supplier
Cas No: 51543-40-9
USD $ 1.2-5.0 / Kiloliter 5 Kiloliter 3000 Metric Ton/Month Chemwill Asia Co., Ltd. Contact Supplier
Cas No: 51543-40-9
No Data 1 Kilogram 100 Kilogram/Day Henan Tianfu Chemical Co., Ltd. Contact Supplier
Manufacturer supply CAS 51543-40-9 with best quality
Cas No: 51543-40-9
USD $ 139.0-210.0 / Kilogram 1 Kilogram 1000 Kilogram/Day Zhuozhou Wenxi import and Export Co., Ltd Contact Supplier
[1,1'-Biphenyl]-4-aceticacid, 2-fluoro-a-methyl-,(aR)- 51543-40-9
Cas No: 51543-40-9
No Data 1 Kilogram 10000 Metric Ton/Month Shanghai Upbio Tech Co.,Ltd Contact Supplier
JSY Trade/Share on googleShare on facebookShare on twitterShare on emailMore Sharing Services high purity Flurbiprofen in stock CAS NO.51543-40-9
Cas No: 51543-40-9
No Data 10 Gram 500 Metric Ton/Month Changchun JuShengyuan Import and Export Trading Co.,Ltd Contact Supplier
Cas No: 51543-40-9
No Data 1 Gram 100 Metric Ton/Day Shanghai Minstar Chemical Co., Ltd Contact Supplier

51543-40-9 Usage


(R)-Flurbiprofen is a COX-inactive enantiomer of the racemic non-selective COX inhibitor flurbiprofen that has diverse biological activities. It inhibits γ-secretase activity in vitro and, in vivo, it reduces formation of amyloid-β peptide 1-42 (Aβ42) and improves axonal transport in young Aβ-plaque free mice but not old mice with existing Aβ plaques in the Tg2576 transgenic model of Alzheimer''s disease. (R)-Flurbiprofen inhibits NF-kB activation and DNA binding as well as AP-1 DNA binding in RAW 264.7 macrophages and reduces paw edema in a rat model of zymosan-induced inflammation via COX-independent inhibition of NF-κB and AP-1 activation when administered at doses of 1, 3, and 9 mg/kg. It also suppresses prostate tumor cell growth in vitro by inducing p75NTR protein expression and reduces tumor growth and metastasis in multiple mouse models of intestinal neoplasia.


(R)-2-Flurbiprofen is the R-isomer of Flurbiprofen (F598700), an anti-inflammatory used as an analgesic.

Biochem/physiol Actions

gamma secretase inhibitor; amyloid Abeta 42 lowering agent

Check Digit Verification of cas no

The CAS Registry Mumber 51543-40-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,5,4 and 3 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 51543-40:
99 % 10 = 9
So 51543-40-9 is a valid CAS Registry Number.

51543-40-9 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Aldrich (545740)  (R)-(−)-2-Fluoro-α-methyl-4-biphenylaceticacid  97% 51543-40-9 545740-1G 1,603.72CNY Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017


1.1 GHS Product identifier

Product name (R)-flurbiprofen

1.2 Other means of identification

Product number -
Other names Flurizan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:51543-40-9 SDS

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