5155-71-5Relevant academic research and scientific papers
Synthesis of 1-benzylcinnoline-3-carboxylic acids
Stanczak, Andrzej
, p. 71 - 76 (2007/10/03)
The method or preparation of 1-benzyl substituted 4-imino- and 4-oxocinnoline-3-carboxylic acids is described. These acids were prepared by alkylation with benzyl bromide of the corresponding ethylcinnoline-3-carboxylates. The esters were hydrolyzed to the desired 1-benzylcinnoline-3-carboxylic acids.
Synthesis of N-benzyl-4-oxo-1,2,3,4-tetrahydrocinnolines
Stanczak, Andrzej
, p. 381 - 387 (2007/10/03)
The method of preparation of N1 and N2-substituted 4-hydroxycinnolines by alkylation with benzyl bromide of the coresponding 4-hydroxycinnolines is described. The obtained derivatives were reduced to the corresponding N-benzyl-4-oxo-l,2,3,4-tetrahydrocinnolines. The effect of some synthesized derivatives on central nervous system was studied.
