51550-28-8

Basic information

• Product Name: (3beta,7alpha)-8-oxo-12,13-epoxytrichothec-9-ene-3,7,15-triyl triacetate
• CAS NO: 51550-28-8
• Molecular Formula: C₂₁H₂₆O₉
• Molecular Weight: 422.4257
• Mol File: 51550-28-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 520.8°C at 760 mmHg
• Flash Point: 225.9°C
• Density: 1.34g/cm³
• Vapor Pressure: 6E-11mmHg at 25°C
• Refractive Index: 1.55
• CAS DataBase Reference: (3beta,7alpha)-8-oxo-12,13-epoxytrichothec-9-ene-3,7,15-triyl triacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (3beta,7alpha)-8-oxo-12,13-epoxytrichothec-9-ene-3,7,15-triyl triacetate(51550-28-8)
• EPA Substance Registry System: (3beta,7alpha)-8-oxo-12,13-epoxytrichothec-9-ene-3,7,15-triyl triacetate(51550-28-8)

Safety Data

• Hazardous Substances Data: 51550-28-8(Hazardous Substances Data)

Usage

General Description

(3beta,7alpha)-8-oxo-12,13-epoxytrichothec-9-ene-3,7,15-triyl triacetate is a complex chemical compound with a molecular structure that includes a trichothecene backbone and three acetate groups attached to various positions. Trichothecenes are a group of mycotoxins produced by various species of fungi, and are known for their toxicity to humans and animals. The specific structure of (3beta,7alpha)-8-oxo-12,13-epoxytrichothec-9-ene-3,7,15-triyl triacetate indicates that it has potential biological activity, possibly related to its ability to interact with cellular processes and enzymes. However, due to its highly complex and potentially hazardous nature, further research is needed to fully understand the properties and potential applications of this compound.

Upstream product

• 119649-05-7 deoxynivalenol tristrimethylsilyl ether 
• 108-24-7 acetic anhydride 
• 50722-38-8 3-acetoxy-7,15-dihydroxy-12,13-epoxytrichothec-9-en-8-one 
• 51481-10-8 vomitoxin hydrate 

Downstream Products

• 88054-24-4 de-epoxy-deoxynivalenol 
• 54996-64-4 7-acetyl-4-deoxynivalenol 
• 54996-63-3 7,15-diacetoxy-4-deoxynivalenol 

Relevant articles and documents

Chemical Deoxygenation of the Trichothecenes Diacetoxyscirpenol and Deoxynivalenol

Based on a model study using the bicyclooctane epoxy acetates (14) and (15), an efficient one-step procedure for the selective removal of the 12,13-epoxide ring of the trichothecene mycotoxins diacetoxyscirpenol (1; R=H) and deoxynivalenol (2; R=H) has been devised.The key to success proved to be use of the lower-valent tungsten deoxygenation system of Sharpless et al.

Chemical Deoxygenation of the Trichothecenes, Diacetoxyscirpenol and Deoxynivalenol

Based on a model study using the bicyclic epoxides (9) and (10), an efficient one-step procedure for the selective removal of the 12,13-epoxide ring of the trichothecene toxins has been devised.

Phytotoxic Compounds Produced by Fusarium equiseti. Part 7. Reactions and Rearrangement of the 7-Hydroxy-12,13-epoxytrichothec-9-en-8-one Skeleton

7α,15-Dihydroxy-12,13-epoxytrichothec-9-en-8-ones, e.g. nivalenol and vomitoxin, rearrange under mild basic conditions to the isomeric 7,13-epoxy-A-nortrichothecane-7-carboxylic acid 15-lactones.With hydrogen chloride, normal addition to the 12,13-epoxide of these compounds occurs, with retention of configuration at C-12, and the more usual rearrangement to the 2β-chloroaprotrichothec-9-en-8-one skeleton is not seen.Catalytic hydrogenation of diacetylnivalenol takes place from the β-face to give correspoding (9R)-trichothecan-8-one.Reliable procedures for the preparation of vomotoxin and nivalenol from their acetates are outlined.