51559-01-4Relevant academic research and scientific papers
Highly regioselective rearrangement of 2,3-diaryl-oxiranes into 2,2-diarylacetaldehydes catalyzed by ytterbium porphyrin complex, Yb(TPP)OTf
Takanami, Toshikatsu,Nakajima, Shin-ichiro,Nakadai, Shoichi,Hino, Fumio,Suda, Kohji
experimental part, p. 365 - 374 (2009/09/06)
[5,10,15,20-Tetraphenylporphynato]ytterbium(III) triflate, Yb(TPP)-OTf, is an efficient Lewis acid catalyst for the highly regioselective rearrangement of 2,3-diaryloxiranes into 2,2-diarylacetaldehydes. The catalytic process can be easily performed not only in dichloroethane but also in a more environmentally friendly solvent, benzotrifluoride.
Tandem pinacol coupling-rearrangement of aromatic aldehydes with hydrogen catalyzed by a combination of a platinum complex and a polyoxometalate
Branytska, Olena,Shimon, Linda J. W.,Neumann, Ronny
, p. 3957 - 3959 (2008/10/09)
Together with a strongly oxidizing polyoxometalate, H5PV 2Mo10O40, PtII(N-(2,6- diisopropylphenyl)pyrazin-2-ylmethanimine)Cl2 forms a combined catalyst that was active in the tandem pinacol coupling-rearrangement of aryl aldehydes to give mostly the corresponding diarylacetaldehyde in high yields using molecular hydrogen as the reducing agent. The Royal Society of Chemistry.
Synthesis and structure-activity relationship studies of novel 2-diarylethyl substituted (2-carboxycycloprop-1-yl)glycines as high-affinity group II metabotropic glutamate receptor ligands.
Sorensen, Ulrik S,Bleisch, Thomas J,Kingston, Anne E,Wright, Rebecca A,Johnson, Bryan G,Schoepp, Darryle D,Ornstein, Paul L
, p. 197 - 205 (2007/10/03)
The major excitatory neurotransmitter in the central nervous system, (S)-glutamic acid , activates both ionotropic and metabotropic excitatory amino acid receptors. Its importance in connection to neurological and psychiatric disorders has directed great
Synthesis of novel GABA uptake inhibitors. 3. Diaryloxime and diarylvinyl ether derivatives of nipecotic acid and guvacine as anticonvulsant agents
Knutsen, Lars J. S.,Andersen, Knud Erik,Lau, Jesper,Lundt, Behrend F.,Henry, Rodger F.,Morton, Howard E.,N?rum, Lars,Petersen, Hans,Stephensen, Henrik,Suzdak, Peter D.,Swedberg, Michael D. B.,Thomsen, Christian,S?rensen, Per O.
, p. 3447 - 3462 (2007/10/03)
(3R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]-3-piperidinecarboxylic acid 1 (tiagabine, Gabitril) is a potent and selective γ-aminobutyric acid (GABA) uptake inhibitor with proven anticonvulsant efficacy in humans. This drug, which has a unique mechanism
