51579-08-9Relevant academic research and scientific papers
Intermolecular cyclization of cinnamoyl isothiocyanate: A new synthetic entry for pyrimidine, triazine, and triazole candidates
El-Sayed, Hassan A.,Abdel Hamid, Atef M.,Assy, Mohamed G.,Faraj, Tahani S.
supporting information, p. 786 - 794 (2018/02/21)
An efficient and facile protocol for the synthesis of azine and azole ring systems was reported. Whereas, reaction of cinnamoyl isothiocyanate with N-nucleophile containing compounds (namely, p-aminophenol (2), N1-phenylbenzene-1,4-diamine (5)
Syntheses of [1,2,4]triazolo[1,5-: A] benzazoles enabled by the transition-metal-free oxidative N-N bond formation
Shang, Erchang,Zhang, Junzhi,Bai, Jinyi,Wang, Zhan,Li, Xiang,Zhu, Bing,Lei, Xiaoguang
supporting information, p. 7028 - 7031 (2016/06/09)
A transition-metal-free oxidative N-N bond formation strategy was developed to generate various structurally interesting [1,2,4]triazolo[1,5-a]benzazoles efficiently. The mechanism of the key oxidative N-N bond formation was investigated by using an intramolecular competition reaction. Notably, the first single crystal structure was also obtained to confirm the structure of 2-aryl[1,2,4]triazolo[1,5-a]benzimidazole.
Synthesis of new triazolo and pyrazolo benzothiazoles
Deshmukh,Patil,Jadhav,Shejwal
, p. 163 - 166 (2013/09/23)
Benzothiazole-2-thiol 1 on heating with excess of hydrazine hydrate yields 2-hydrazino-1,3-benzothiazole (2). Compound 2 on reaction with carbon disulfide in alkaline medium affords [1,2,4] triazolo [3,4-b] [1,3] benzothiazole-3-thiol (3). Condensation of 2 with various substituted aryl aldehydes yields corresponding hydrazine derivatives (4), which on cyclisation with acetic anhydride gave corresponding [1,2,4] triazolo [3,4-6] [1,3] benzothiazoles (5). Some other triazolo derivatives (6,7,8) of benzothiazole were obtained by the cyclization of 2 with benzoyl chloride, acetyl chloride and formic acid respectively. Again compound 2 on condensation with acetyl acetone and ethylacetoacetate gives pyrazolo derivatives (9,10) respectively. The synthesized compounds were characterized by elemental and spectral analysis.
Synthesis, Photolysis and Pyrolysis of 1-(2'-Benzothiazolyl)-5-aryltetrazoles
Kamala, K.,Rao, P. Jayaprasad,Reddy, K. Kondal
, p. 1194 - 1196 (2007/10/02)
Aroylaminobenzothiazoles (II), have been converted into 1-(2'-benzothiazolyl)-5-aryltetrazoles (IV) by treatment with PCl5 followed by azidolysis with sodium azide in aequeous acetone solution.Pyrolysis of IV in tetralin affords exclusively 2-aryl-s-triaz
