515824-05-2

Basic information

• Product Name: (1'R,2S,3S,4S)-(1,4-dimethyl-3-phenylazetidin-2-yl)phenylmethanol
• Synonyms: (1'R,2S,3S,4S)-(1,4-dimethyl-3-phenylazetidin-2-yl)phenylmethanol
• CAS NO: 515824-05-2
• Molecular Weight: 267.371
• Mol File: 515824-05-2.mol

Chemical Properties

• CAS DataBase Reference: (1'R,2S,3S,4S)-(1,4-dimethyl-3-phenylazetidin-2-yl)phenylmethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (1'R,2S,3S,4S)-(1,4-dimethyl-3-phenylazetidin-2-yl)phenylmethanol(515824-05-2)
• EPA Substance Registry System: (1'R,2S,3S,4S)-(1,4-dimethyl-3-phenylazetidin-2-yl)phenylmethanol(515824-05-2)

Safety Data

• Hazardous Substances Data: 515824-05-2(Hazardous Substances Data)

Upstream product

• 515824-01-8 (2S,3S,4S)-(1,4-dimethyl-3-phenylazetidin-2-yl)phenylmethanone 
• 591-51-5 phenyllithium 
• 452096-24-1 (2R,3S,4S)-1,4-dimethyl-3-phenyl-azetidine-2-carbonitrile 
• 452096-25-2 (2S,3S,4S)-1,4-dimethyl-3-phenyl-azetidine-2-carbonitrile 
• 515824-00-7 C-(1,4-dimethyl-3-phenyl-azetidin-2-yl)-C-phenyl-methyleneamine 
• 515823-98-0 C-(1,4-dimethyl-3-phenyl-azetidin-2-yl)-C-phenyl-methyleneamine 

Downstream Products

• 1052670-46-8 3-azido-1,5-dimethyl-2,4-diphenylpyrrolidine 
• 15364-06-4 1,5-dimethyl-2,4-diphenylpyrrole 
• 1052670-25-3 3-hydroxy-1,5-dimethyl-2,4-diphenylpyrrolidine 
• 1052670-06-0 (2S,3R,4S,5S)-3-chloro-1,5-dimethyl-2,4-diphenylpyrrolidine 
• 1052670-05-9 C₁₉H₂₃NO₃S 
• 1047987-92-7 C₁₈H₂₀FN 
• 1052670-31-1 3-cyano-1,5-dimethyl-2,4-diphenylpyrrolidine 

Relevant articles and documents

Synthesis of enantiopure 2-acyl azetidines and the application of amino alcohols derived therefrom in enantioselective catalysis

Enantiopure 2-acyl azetidines were prepared in good yields from 2-cyano azetidines. The ketones produced were then stereoselectively reduced with sodium borohydride (with or without zinc bromide) or transformed into tertiary azetidinic amino alcohols by addition of phenyllithium. The latter compounds were found to be highly efficient catalysts for the enantioselective addition of diethylzinc to aldehydes, giving enantioselectivities up to 98%.