515835-47-9

Upstream product

• 115186-34-0 tert-butyl ((S)-3-(benzyloxy)-1-(methoxy(methyl)amino)-1-oxopropan-2-yl)carbamate 
• 120-92-3 cyclopentanone 
• 23680-31-1 BOC-O-benzyl-L-serine 
• 10080-41-8 cyclopentanone hydrazone 
• 17497-52-8 1-iodocyclopentene 
• 515835-39-9 (1-benzyloxymethyl-2-cyclopent-1-enyl-2-oxo-ethyl)-carbamic acid tert-butyl ester 

Downstream Products

• 345341-71-1 (R)-2-[(R)-2-(Benzyl-tert-butoxycarbonyl-amino)-3-benzyloxy-prop-(Z)-ylidene]-cyclopentanecarboxylic acid 
• 345341-69-7 Benzyl-{(R)-1-benzyloxymethyl-2-[(R)-2-hydroxymethyl-cyclopent-(Z)-ylidene]-ethyl}-carbamic acid tert-butyl ester 
• 345341-65-3 (1S,2S)-3-Benzyloxy-1-cyclopent-1-enyl-2-dibenzylamino-propan-1-ol 
• 515835-51-5 {(R)-2-[(R)-2-Benzylamino-3-benzyloxy-prop-(Z)-ylidene]-cyclopentyl}-methanol 
• 345341-68-6 {(R)-2-[(R)-3-Benzyloxy-2-dibenzylamino-prop-(Z)-ylidene]-cyclopentyl}-methanol 

Relevant academic research and scientific papers

ALKENE MIMICS

Ac-Phe-Tyr-phosphoSer-Ψ[CH=C]-Pro-Arg-NH2AND Fmoc-bis(pivaloylmethoxy)phosphoSer-Ψ[CH=C]-Pro-2-aminoethyl-(3-indole); and their Phospho-(D)-serine stereoisomers are novel compounds. Ψ refers to a pseudo amide. Such novel compounds advantageousl

Serine-cis-proline and serine-trans-proline isosteres: Stereoselective synthesis of (Z)- and (E)-alkene mimics by Still-Wittig and Ireland-Claisen rearrangements

Two new amide isosteres of Ser-cis-Pro and Ser-trans-Pro dipeptides were designed and stereo-selectively synthesized to be incorporated into potential inhibitors of the phosphorylation-dependent peptidylprolyl isomerase Pin1, an essential regulator of the