345341-65-3

Upstream product

• 23680-31-1 BOC-O-benzyl-L-serine 
• 515835-39-9 (1-benzyloxymethyl-2-cyclopent-1-enyl-2-oxo-ethyl)-carbamic acid tert-butyl ester 
• 350996-27-9 2-amino-3-benzyloxy-N-methoxy-N-methyl-propionamide 
• 120-92-3 cyclopentanone 
• 10080-41-8 cyclopentanone hydrazone 
• 17497-52-8 1-iodocyclopentene 
• 345341-64-2 (S)-3-Benzyloxy-1-cyclopent-1-enyl-2-dibenzylamino-propan-1-one 
• 100-39-0 benzyl bromide 
• 131150-31-7 (S)-3-benzyloxy-2-(dibenzylamino)-N'-methoxy-N'-methylpropane amide 
• 115186-34-0 tert-butyl ((S)-3-(benzyloxy)-1-(methoxy(methyl)amino)-1-oxopropan-2-yl)carbamate 
• 515835-47-9 ((1S,2S)-1-Benzyloxymethyl-2-cyclopent-1-enyl-2-hydroxy-ethyl)-carbamic acid tert-butyl ester 

Downstream Products

• 345341-68-6 {(R)-2-[(R)-3-Benzyloxy-2-dibenzylamino-prop-(Z)-ylidene]-cyclopentyl}-methanol 
• 345341-66-4 Dibenzyl-((1S,2S)-1-benzyloxymethyl-2-cyclopent-1-enyl-2-tributylstannanylmethoxy-ethyl)-amine 
• 345341-71-1 (R)-2-[(R)-2-(Benzyl-tert-butoxycarbonyl-amino)-3-benzyloxy-prop-(Z)-ylidene]-cyclopentanecarboxylic acid 
• 345341-69-7 Benzyl-{(R)-1-benzyloxymethyl-2-[(R)-2-hydroxymethyl-cyclopent-(Z)-ylidene]-ethyl}-carbamic acid tert-butyl ester 
• 515835-51-5 {(R)-2-[(R)-2-Benzylamino-3-benzyloxy-prop-(Z)-ylidene]-cyclopentyl}-methanol 

Relevant academic research and scientific papers

ALKENE MIMICS

Ac-Phe-Tyr-phosphoSer-Ψ[CH=C]-Pro-Arg-NH2AND Fmoc-bis(pivaloylmethoxy)phosphoSer-Ψ[CH=C]-Pro-2-aminoethyl-(3-indole); and their Phospho-(D)-serine stereoisomers are novel compounds. Ψ refers to a pseudo amide. Such novel compounds advantageousl

Serine-cis-proline and serine-trans-proline isosteres: Stereoselective synthesis of (Z)- and (E)-alkene mimics by Still-Wittig and Ireland-Claisen rearrangements

Two new amide isosteres of Ser-cis-Pro and Ser-trans-Pro dipeptides were designed and stereo-selectively synthesized to be incorporated into potential inhibitors of the phosphorylation-dependent peptidylprolyl isomerase Pin1, an essential regulator of the

Solvent-dependent stereoselectivity in a Still-Wittig rearrangement: An experimental and ab initio study

(formula presented) The Still-Wittig rearrangement gave opposite selectivities for (Z:E)-alkenes in THF (3:1) vs toluene (1:3) in the synthesis of serine-proline dipeptide amide isosteres. Four transition states leading to (Z)-and (E)-alkenes with THF and