515875-36-2Relevant articles and documents
Synthesis and biological activity of 3-(2-furanyl)-6-aryl-1,2,4-triazolo[3, 4-b]-1,3,4-thiadiazoles
Zhang, Li-Xue,Zhang, An-Jiang,Chen, Xian-Xing,Lei, Xin-Xiang,Nan, Xiang-Yun,Chen, Dong-Yong,Zhang, Zi-Yi
, p. 681 - 689 (2007/10/03)
3-(2-Furanyl)-4-amino-5-mercapto-1,2,4-triazole (1) was prepared from 2-furoic acid through a multi-step reaction sequence. Compound 1 reacted with aromatic acids in the presence of phosphorus oxychloride to give 3-(2-furanyl)-6-aryl-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles (2). The structures of all the newly synthesized compounds have been confirmed by elemental analysis, IR, 1H-NMR, 13C-NMR and mass spectra. The bioassay indicated most of the title compounds possess significant growth promoting effects on mung bean radicles.