515883-93-9

Basic information

• Product Name: 6-(2-chlorophenyl)-3-[1-(4-isobutylphenyl)ethyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
• CAS NO: 515883-93-9
• Molecular Weight: 396.944
• Mol File: 515883-93-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-(2-chlorophenyl)-3-[1-(4-isobutylphenyl)ethyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(2-chlorophenyl)-3-[1-(4-isobutylphenyl)ethyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(515883-93-9)
• EPA Substance Registry System: 6-(2-chlorophenyl)-3-[1-(4-isobutylphenyl)ethyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole(515883-93-9)

Safety Data

• Hazardous Substances Data: 515883-93-9(Hazardous Substances Data)

Upstream product

• 515883-91-7 4-amino-5-[1-(4-isobutylphenyl)ethyl]-3-mercapto-(4H)-1,2,4-triazole 
• 118-91-2 ortho-chlorobenzoic acid 

Relevant articles and documents

Microwave-mediated synthesis of triazolothiadiazoles as anti-inflammatory, analgesic, and anti-oxidant agents

Efficient approach to the synthesis of a series of triazolothiadiazole analogs of ibuprofen has been carried out using microwave energy. Thus a series of 1,2,4-triazolo[3,4-b]-thiadiazoles 5 were synthesized starting from 4-amino-3-[1-(4-isobutylphenyl)ethyl]-5-mercapto-1,2,4-triazole 3 and different aromatic acids using phosphorous oxychloride as cyclizing agent by microwave and conventional method. Microwave irradiation reduces both time and reaction endeavors along with reduced amount of phosphorous oxychloride. In addition, preliminary results of the biological evaluation of these compounds are also reported and they found to exhibit significant antioxidant, anti-inflammatory, and analgesic activities with reduced ulcerogenicity. Springer Science+Business Media, LLC 2011.