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ALPHA-CORTOLONE, also known as α-Cortolone, is a human urinary metabolite of Cortisol, a steroid hormone belonging to the glucocorticoid class. It is produced by the zona fasciculata of the adrenal gland and plays a crucial role in the body's response to stress and maintaining blood glucocorticoid levels. ALPHA-CORTOLONE is involved in various physiological processes, including increasing blood sugar through gluconeogenesis, suppressing the immune system, and aiding in the metabolism of fat, protein, and carbohydrates.

516-42-7

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516-42-7 Usage

Uses

Used in Pharmaceutical Industry:
ALPHA-CORTOLONE is used as a therapeutic agent for various medical conditions due to its glucocorticoid properties. It helps in managing inflammation, immune system suppression, and facilitating the metabolism of essential nutrients.
Used in Stress Management:
ALPHA-CORTOLONE is used as a biomarker for stress management, as it is a metabolite of Cortisol, which is released in response to stress. Monitoring the levels of ALPHA-CORTOLONE in the body can provide insights into an individual's stress levels and help in developing appropriate stress management strategies.
Used in Metabolic Research:
ALPHA-CORTOLONE is used as a research tool in the study of metabolic processes, particularly in the context of fat, protein, and carbohydrate metabolism. Understanding the role of ALPHA-CORTOLONE in these processes can contribute to the development of treatments for metabolic disorders and other related health issues.
Used in Immunology Research:
ALPHA-CORTOLONE is used as a research tool in immunology, as it plays a role in suppressing the immune system. Studying the interactions of ALPHA-CORTOLONE with the immune system can help in the development of novel immunosuppressive therapies and a better understanding of immune system regulation.

Check Digit Verification of cas no

The CAS Registry Mumber 516-42-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,1 and 6 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 516-42:
(5*5)+(4*1)+(3*6)+(2*4)+(1*2)=57
57 % 10 = 7
So 516-42-7 is a valid CAS Registry Number.
InChI:InChI=1/C21H34O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12-15,17-18,22-23,25-26H,3-11H2,1-2H3/t12?,13-,14+,15+,17-,18-,19+,20+,21+/m1/s1

516-42-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (3R,5R,8S,9S,10S,13S,14S,17R)-17-[(1S)-1,2-dihydroxyethyl]-3,17-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one

1.2 Other means of identification

Product number -
Other names Cortolon

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:516-42-7 SDS

516-42-7Downstream Products

516-42-7Relevant academic research and scientific papers

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