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p-TosOH*H-Phe-ODpm is a complex chemical compound consisting of three main components: p-toluenesulfonic acid (p-TosOH), hydroxyphenylalanine (H-Phe), and 2,2-dimethoxypropane (ODpm). p-Toluenesulfonic acid is a strong acid used as a catalyst in various organic reactions, while hydroxyphenylalanine is a derivative of phenylalanine, an essential amino acid. The ODpm group serves as a protecting group for the hydroxyl group in hydroxyphenylalanine, preventing unwanted side reactions. p-TosOH*H-Phe-ODpm is often used in peptide synthesis and organic chemistry, where the p-TosOH acts as a catalyst, and the H-Phe-ODpm moiety provides a protected amino acid building block for the formation of peptides or other complex molecules.

5160-06-5

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5160-06-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5160-06-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,6 and 0 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5160-06:
(6*5)+(5*1)+(4*6)+(3*0)+(2*0)+(1*6)=65
65 % 10 = 5
So 5160-06-5 is a valid CAS Registry Number.

5160-06-5Downstream Products

5160-06-5Relevant academic research and scientific papers

Application of 4-Polystyryltriphenylmethyl Chloride to the Syntheses of Peptides and Amino Acid Derivatives

Barlos, Kleomenis,Gatos, Dimitrios,Kallitsis, Ioannis,Papaioannou, Dionysios,Sotiriou, Petros

, p. 1079 - 1082 (2007/10/02)

Use of polymer-bound trityl chloride as an α-amino protecting group of amino acids allows simple and high-yield syntheses of amino acid derivatives and peptides.

A Novel Preparation of Amino Acid Diphenylmethyl Esters and Their Application in Peptide Synthesis

Barlos, Kleomenis,Kallitsis, John,Mamos, Petros,Patrianakou, Stella,Stavropoulos, Georg

, p. 633 - 636 (2007/10/02)

Trityl amino acid diphenylmethyl esters 2 were prepared by Mitsunobu condensation of tritylamino acids 1 with diphenylmethanol using excess triphenylphosphane and diethyl azodicarboxylate.The esters 2 were converted into the corresponding p-toluenesulfonates 3 on treatment with p-toluenesulfonic acid.The removal of the N-trityl group in the presence of the diphenylmethyl ester group is studied by the preparation of leucine-enkephalin (12).Best selectivity is obtained when 1-hydroxybenzotriazole in trifluoroethanol is used as detritylation reagent.

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