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2,4-Dihydroxy-6-MethylpyriMidine-5-carboxylic acid, also known as thymine, is a pyrimidine derivative with the chemical formula C7H8N2O5. It is one of the four nucleobases that constitute DNA, alongside adenine, cytosine, and guanine. Thymine plays a vital role in the genetic code by pairing with adenine through hydrogen bonds, ensuring the accurate replication and transcription of genetic information. As a crucial component in the synthesis of nucleic acids, thymine serves as an essential building block for the formation of DNA molecules.

51622-67-4

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51622-67-4 Usage

Uses

Used in DNA Synthesis:
2,4-Dihydroxy-6-MethylpyriMidine-5-carboxylic acid is used as a nucleobase in DNA synthesis for its critical role in the genetic code. It pairs with adenine through hydrogen bonds, ensuring the accurate replication and transcription of genetic information.
Used in Genetic Research:
In the field of genetic research, 2,4-Dihydroxy-6-MethylpyriMidine-5-carboxylic acid is used as a fundamental component for studying DNA structure, function, and mutations. Its role in base pairing and replication provides insights into the mechanisms of genetic inheritance and the development of genetic disorders.
Used in Pharmaceutical Industry:
2,4-Dihydroxy-6-MethylpyriMidine-5-carboxylic acid is utilized in the pharmaceutical industry for the development of drugs targeting DNA synthesis and repair mechanisms. Its involvement in DNA replication and transcription makes it a potential candidate for therapeutic interventions in diseases associated with genetic mutations or DNA damage.
Used in Diagnostics:
In diagnostics, 2,4-Dihydroxy-6-MethylpyriMidine-5-carboxylic acid is employed as a biomarker for detecting DNA damage or mutations. Its presence and modifications can indicate the presence of certain genetic disorders or the effectiveness of therapeutic interventions targeting DNA repair mechanisms.
Used in Forensic Science:
2,4-Dihydroxy-6-MethylpyriMidine-5-carboxylic acid, as a component of DNA, is used in forensic science for DNA profiling and identification. Its unique sequence and pairing properties allow for the analysis of genetic material found in crime scene samples, aiding in the resolution of criminal investigations.

Check Digit Verification of cas no

The CAS Registry Mumber 51622-67-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,6,2 and 2 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 51622-67:
(7*5)+(6*1)+(5*6)+(4*2)+(3*2)+(2*6)+(1*7)=104
104 % 10 = 4
So 51622-67-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H6N2O4/c1-2-3(5(10)11)4(9)8-6(12)7-2/h1H3,(H,10,11)(H2,7,8,9,12)

51622-67-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-methyl-2,4-dioxo-1H-pyrimidine-5-carboxylic acid

1.2 Other means of identification

Product number -
Other names 2,4-Dihydroxy-6-methyl-5-pyrimidinecarboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:51622-67-4 SDS

51622-67-4Downstream Products

51622-67-4Relevant academic research and scientific papers

Pyrimidine carboxamides and related compounds and methods for treating inflammatory conditions

-

, (2008/06/13)

Compounds having utility as antinflammatory agents in general and, more specifically, for the prevention and/or treatment of immunoinflammatory and autoimmune diseases are disclosed. The compounds are pyrimidine- or pyrazine-containing compounds and, in one embodiment, are carboxyamides of the same. Methods are also disclosed for preventing and/or treating inflammatory conditions by administering to an animal in need thereof an effective amount of a compound of this invention, preferably in the form of a pharmaceutical composition.

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